Most Read Articles
01 Apr 2013
Aspergillus colonization may lead to an increase in the risk of bronchiolitis obliterans syndrome. This study determined the impact of colonization of conidia Aspergillus species after post lung transplantation.
3 days ago
No standard currently exists for the growing number of patients with multidrug-resistant strains of Helicobacter pylori, but a recent study has shown the safety and reliability of a 12-day low-dose rifabutin/high-dose proton pump inhibitor (PPI) regimen in patients infected with triple-resistant strains.
Roshini Claire Anthony, 10 Jan 2018

Adding rifampicin to standard antibiotic therapy does not improve outcomes in individuals with Staphylococcus aureus (S. aureus) bacteraemia, the ARREST* trial shows. However, rifampicin may contribute towards a minor reduction in bacteraemia recurrence.

5 days ago
Patients with a first episode of Clostridium difficile infection (CDI) are likely to respond to treatment with fidaxomicin with no recurrences, a recent study has shown. On the other hand, those with prior CDI episodes are less likely to respond, especially with >1 prior episode, and more likely to recur, which suggests a greater clinical benefit of fidaxomicin earlier in the course of CDI.

Targeted intervention improves vaccination rate of asplenic patients

06 Jul 2017
The pharmacy tech allegedly syringed out 252 vials of fentanyl and replaced the contents with normal saline.

Guideline-based care for asplenic patients can be improved by targeted interventions, a recent study suggests. Furthermore, three of four recommended vaccinations have increased with the creation of a clinic designed for asplenic patients.

To show that a targeted intervention can improve vaccination rates in a population of asplenic veterans, researchers identified surgically asplenic patients actively receiving care via a database search. Letters were mailed to these individuals, encouraging them to attend an existing travel clinic with a new process designed for asplenic patients.

Patients were given further education on the risks of asplenia and proper preventive precautions in the said clinic. In addition, vaccination history was obtained, and patients were administered any additional indicated vaccines.

A total of 113 patients were identified from the database search. Providers identified and referred an additional 14 asplenic patients to the travel clinic, and two were referred prior to the planned splenectomy. The first-year referral rate to the clinic was 29 percent (38 of 129 asplenic patients).

The first year of the intervention resulted in increases in the rates of three of four recommended vaccinations: pneumococcal conjugate (19 to 55 percent; p<0.001); Haemophilus influenza type B (19 to 35 percent; p=0.007); and meningococcal vaccine (24 to 43 percent; p=0.002). The rate of pneumococcal polysaccharide vaccination rose from 91 to 93 percent (p=0.62).

The use of targeted intervention may be applicable to other healthcare systems with similar numbers of asplenic patients, according to researchers.

“Asplenic patients are at risk for severe infections, but adherence to recommended preventive education and vaccination is poor,” they added.

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Most Read Articles
01 Apr 2013
Aspergillus colonization may lead to an increase in the risk of bronchiolitis obliterans syndrome. This study determined the impact of colonization of conidia Aspergillus species after post lung transplantation.
3 days ago
No standard currently exists for the growing number of patients with multidrug-resistant strains of Helicobacter pylori, but a recent study has shown the safety and reliability of a 12-day low-dose rifabutin/high-dose proton pump inhibitor (PPI) regimen in patients infected with triple-resistant strains.
Roshini Claire Anthony, 10 Jan 2018

Adding rifampicin to standard antibiotic therapy does not improve outcomes in individuals with Staphylococcus aureus (S. aureus) bacteraemia, the ARREST* trial shows. However, rifampicin may contribute towards a minor reduction in bacteraemia recurrence.

5 days ago
Patients with a first episode of Clostridium difficile infection (CDI) are likely to respond to treatment with fidaxomicin with no recurrences, a recent study has shown. On the other hand, those with prior CDI episodes are less likely to respond, especially with >1 prior episode, and more likely to recur, which suggests a greater clinical benefit of fidaxomicin earlier in the course of CDI.