Most Read Articles
Elvira Manzano, 4 days ago

The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.

Pearl Toh, 5 days ago
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.
Yesterday
Cryptococcosis is more common in nonhuman immunodeficiency virus (HIV) nontransplant (NHNT) patients, and this population tends to have more localized pulmonary cryptococcosis and significantly higher 90-day mortality, reports a study.
5 days ago
Type 2 diabetes (T2D) is an independent risk factor for all-cause dementia, with the greatest risk observed in patients who are insulin-dependent and obese, a recent study has found.

Systolic blood pressure factors in subarachnoid haemorrhage but not in intracranial aneurysm

19 Aug 2019

Systolic blood pressure appears to have a strong association with aneurysmal subarachnoid haemorrhage (aSAH) but not with unruptured intracranial aneurysm (UIA), whereas current smoking and female sex are risk factors for both conditions, a study has found.

The study included 89,951 individuals who had standardized measurements of blood pressure and completed self-administered questionnaires. UIA occurred in 97 individuals and aSAH in 117. The corresponding detection rates were 8.2 and 9.9 per 100,000 person-years.

On Cox regression analysis, UIA risk was significantly high in individuals who currently smoked (hazard ratio [HR], 4.1, 95 percent CI, 2.4–7.1) and in women (HR, 2.8, 1.7–4.5). There was no association found for systolic blood pressure (p-trend=0.62).

On the other hand, the most important risk factors for aSAH were current smoking (HR, 3.4, 2.2–5.4), female sex (HR, 1.8, 1.2–2.7) and increasing systolic blood pressure (p-trend=0.006).

Contrary to previous studies reporting an association between hypertension and UIA, the current study collected potential risk factors before and not at the time of UIA detection, making reverse causation unlikely, researchers pointed out. [Stroke 2015;46:3093-3098; Stroke 2013;44:984-987; Int J Stroke 2016;11:917-927]

The current data thus indicate that systolic blood pressure may be associated with rupture but not formation of intracranial aneurysms, they added.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Elvira Manzano, 4 days ago

The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.

Pearl Toh, 5 days ago
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.
Yesterday
Cryptococcosis is more common in nonhuman immunodeficiency virus (HIV) nontransplant (NHNT) patients, and this population tends to have more localized pulmonary cryptococcosis and significantly higher 90-day mortality, reports a study.
5 days ago
Type 2 diabetes (T2D) is an independent risk factor for all-cause dementia, with the greatest risk observed in patients who are insulin-dependent and obese, a recent study has found.