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2 days ago
Use of potassium citrate and thiazides appears to improve health-related quality of life (HRQOL) among stone formers across all Wisconsin Stone Quality of Life (WISQOL) domains without increasing the likelihood of gastrointestinal complaints and fatigue or sexual complaints, respectively, reports a study.
Pearl Toh, 6 days ago
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3 days ago
Eating high amounts of red and processed meat prior to a diagnosis of colorectal cancer appears to be associated with shorter survival time, although a possible weak association cannot be excluded, a study has shown.
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Middle-aged Caucasian men who are dissatisfied with their marriage are at higher risk of sudden cardiac death regardless of other cardiovascular risk factors, a new study reports.

Survival in HPV-associated cancers vary by age, race

14 Nov 2017

The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.

Survival data from 27 population-based US cancer registries were retrieved and used in the analysis. Only cases of invasive cancers that fulfilled the criteria for HPV association were included. The overall and relative 5-year survival rates were calculated for patients diagnosed from 2001 to 2011.

In the study sample of 220,211 patients with HPV-associated cancers, the most common cancer types were oropharyngeal squamous cell carcinomas (SCCs) and cervical carcinomas, observed in 36.4 and 36.1 percent, respectively.

These were followed by anal SCCs (11.8 percent), vulvar SCCs (8.8 percent), penile SCCs (2.8 percent), vaginal SCCs (2.2 percent) and rectal SCCs (1.9 percent).

Five-year age-standardized survival rates were highest for vulvar (66 percent) and anal (65.9 percent) SCCs. In contrast, penile (47.4 percent) and oropharyngeal (51.2 percent) SCCs had the lowest survival rates out of all included cancer types.

Survival for cervical carcinomas, penile SCCs and oropharyngeal SCCs consistently declined with increasing age. On the other hand, those diagnosed with vaginal, vulvar and anal SCCs between the ages of 40 and 49 years had slightly higher survival than those diagnosed at <40 years.

Five-year age-standardized relative survival was higher in Caucasians than African-Americans for cervical carcinomas (64.8 vs 57 percent), penile SCCs (48.4 vs 34.7 percent), anal SCCs (69.3 vs 59.8 percent), rectal SCCs (61.2 vs 45.5 percent) and oropharyngeal SCCs (53.5 vs 32.4 percent).

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Most Read Articles
2 days ago
Use of potassium citrate and thiazides appears to improve health-related quality of life (HRQOL) among stone formers across all Wisconsin Stone Quality of Life (WISQOL) domains without increasing the likelihood of gastrointestinal complaints and fatigue or sexual complaints, respectively, reports a study.
Pearl Toh, 6 days ago
First-line therapy with the BTK* inhibitor ibrutinib plus the anti-CD20 immunotherapy rituximab confers significant survival advantage over the current gold-standard regimen of fludarabine, cyclophosphamide, and rituximab (FCR) for young, fit patients with treatment-naïve chronic lymphocytic leukaemia (CLL), according to the E1912 trial, a large cooperative group study supported by the US National Cancer Institute.
3 days ago
Eating high amounts of red and processed meat prior to a diagnosis of colorectal cancer appears to be associated with shorter survival time, although a possible weak association cannot be excluded, a study has shown.
3 days ago
Middle-aged Caucasian men who are dissatisfied with their marriage are at higher risk of sudden cardiac death regardless of other cardiovascular risk factors, a new study reports.