Most Read Articles
12 Jun 2018
Percutaneous coronary intervention (PCI) is a safe procedure to perform on obese and morbidly obese patients, a recent study has shown.
Roshini Claire Anthony, 11 Jun 2018

Patients who received a combination of ticagrelor plus aspirin within 24 hours of undergoing coronary artery bypass grafting (CABG) had significantly improved saphenous vein graft patency rates 1 year post-procedure compared with those who only received aspirin, according to findings of the DACAB* trial.

4 days ago
Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.
4 days ago
Use of quetiapine among critically ill patients rarely leads to corrected QT (QTc) interval prolongation, reports a new study.

Survival in HPV-associated cancers vary by age, race

14 Nov 2017

The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.

Survival data from 27 population-based US cancer registries were retrieved and used in the analysis. Only cases of invasive cancers that fulfilled the criteria for HPV association were included. The overall and relative 5-year survival rates were calculated for patients diagnosed from 2001 to 2011.

In the study sample of 220,211 patients with HPV-associated cancers, the most common cancer types were oropharyngeal squamous cell carcinomas (SCCs) and cervical carcinomas, observed in 36.4 and 36.1 percent, respectively.

These were followed by anal SCCs (11.8 percent), vulvar SCCs (8.8 percent), penile SCCs (2.8 percent), vaginal SCCs (2.2 percent) and rectal SCCs (1.9 percent).

Five-year age-standardized survival rates were highest for vulvar (66 percent) and anal (65.9 percent) SCCs. In contrast, penile (47.4 percent) and oropharyngeal (51.2 percent) SCCs had the lowest survival rates out of all included cancer types.

Survival for cervical carcinomas, penile SCCs and oropharyngeal SCCs consistently declined with increasing age. On the other hand, those diagnosed with vaginal, vulvar and anal SCCs between the ages of 40 and 49 years had slightly higher survival than those diagnosed at <40 years.

Five-year age-standardized relative survival was higher in Caucasians than African-Americans for cervical carcinomas (64.8 vs 57 percent), penile SCCs (48.4 vs 34.7 percent), anal SCCs (69.3 vs 59.8 percent), rectal SCCs (61.2 vs 45.5 percent) and oropharyngeal SCCs (53.5 vs 32.4 percent).

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Most Read Articles
12 Jun 2018
Percutaneous coronary intervention (PCI) is a safe procedure to perform on obese and morbidly obese patients, a recent study has shown.
Roshini Claire Anthony, 11 Jun 2018

Patients who received a combination of ticagrelor plus aspirin within 24 hours of undergoing coronary artery bypass grafting (CABG) had significantly improved saphenous vein graft patency rates 1 year post-procedure compared with those who only received aspirin, according to findings of the DACAB* trial.

4 days ago
Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.
4 days ago
Use of quetiapine among critically ill patients rarely leads to corrected QT (QTc) interval prolongation, reports a new study.