Most Read Articles
2 days ago
The types of bariatric surgery differentially affect the risk of developing acute pancreatitis postoperatively, such that the risk is greater in patients who undergo vertical sleeve gastrectomy vs Roux-en-Y gastric bypass surgery, according to a study. Risk factors include younger age and presence of gallstones.
6 days ago
Elderly adults using hypoglycaemic glucose-lowering drugs, such as insulin and glinides, have an excess risk of hospitalization for serious trauma, a recent study has found.
6 days ago
Rather than the presence or type or urinary incontinence, increasing severity of urinary incontinence correlates with increased depression, anxiety and stress among treatment-seeking women with lower urinary tract symptoms (LUTS), suggests a study.
Roshini Claire Anthony, 4 days ago

Overweight or obese patients taking lorcaserin as an appetite suppressant may have the added benefit of a reduced risk of incident diabetes, according to results of the CAMELLIA-TIMI 61* trial presented at EASD 2018.

Survival in HPV-associated cancers vary by age, race

14 Nov 2017

The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.

Survival data from 27 population-based US cancer registries were retrieved and used in the analysis. Only cases of invasive cancers that fulfilled the criteria for HPV association were included. The overall and relative 5-year survival rates were calculated for patients diagnosed from 2001 to 2011.

In the study sample of 220,211 patients with HPV-associated cancers, the most common cancer types were oropharyngeal squamous cell carcinomas (SCCs) and cervical carcinomas, observed in 36.4 and 36.1 percent, respectively.

These were followed by anal SCCs (11.8 percent), vulvar SCCs (8.8 percent), penile SCCs (2.8 percent), vaginal SCCs (2.2 percent) and rectal SCCs (1.9 percent).

Five-year age-standardized survival rates were highest for vulvar (66 percent) and anal (65.9 percent) SCCs. In contrast, penile (47.4 percent) and oropharyngeal (51.2 percent) SCCs had the lowest survival rates out of all included cancer types.

Survival for cervical carcinomas, penile SCCs and oropharyngeal SCCs consistently declined with increasing age. On the other hand, those diagnosed with vaginal, vulvar and anal SCCs between the ages of 40 and 49 years had slightly higher survival than those diagnosed at <40 years.

Five-year age-standardized relative survival was higher in Caucasians than African-Americans for cervical carcinomas (64.8 vs 57 percent), penile SCCs (48.4 vs 34.7 percent), anal SCCs (69.3 vs 59.8 percent), rectal SCCs (61.2 vs 45.5 percent) and oropharyngeal SCCs (53.5 vs 32.4 percent).

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Most Read Articles
2 days ago
The types of bariatric surgery differentially affect the risk of developing acute pancreatitis postoperatively, such that the risk is greater in patients who undergo vertical sleeve gastrectomy vs Roux-en-Y gastric bypass surgery, according to a study. Risk factors include younger age and presence of gallstones.
6 days ago
Elderly adults using hypoglycaemic glucose-lowering drugs, such as insulin and glinides, have an excess risk of hospitalization for serious trauma, a recent study has found.
6 days ago
Rather than the presence or type or urinary incontinence, increasing severity of urinary incontinence correlates with increased depression, anxiety and stress among treatment-seeking women with lower urinary tract symptoms (LUTS), suggests a study.
Roshini Claire Anthony, 4 days ago

Overweight or obese patients taking lorcaserin as an appetite suppressant may have the added benefit of a reduced risk of incident diabetes, according to results of the CAMELLIA-TIMI 61* trial presented at EASD 2018.