Most Read Articles
Roshini Claire Anthony, 5 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 09 Nov 2018
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
3 days ago
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.
Pearl Toh, 08 Nov 2018
The pneumonia-causing bacteria, Streptococcus pneumoniae (pneumococcus), can be spread through nose picking and rubbing after exposure of the hands to the bacteria — in addition to the conventionally known route of inhalation of airborne droplets, a study reveals.

Surgical resection superior to radiofrequency ablation for small perivascular HCC

22 Jun 2018

Surgical resection (SR) as a first-line treatment for small perivascular hepatocellular carcinoma (HCC) provides better long-term tumour control than radiofrequency ablation (RFA), a recent study has shown.

Researchers performed a retrospective study of 283 consecutive small perivascular HCC patients who received either SR (n=182; mean age 53.8±9.2 years; 77.5 percent male) or RFA (n=101; mean age 57.0±10.0 years; 77.2 percent male) first-line treatment. Progression-free survival (PFS) and overall survival (OS) were compared between the two groups.

After propensity score matching (n=62 for each group), those who received SR showed significantly better survival than their RFA counterparts. The 3-, 5-, 7- and 10-year PFS rates were 68.7 percent, 58.0 percent, 56.0 percent and 17.8 percent in the SR group and 41.2 percent, 25.4 percent, 14.1 percent and 14.1 percent in the RDFA group, respectively (p<0.001).

A similar trend was observed for the 3-, 5-, 7- and 10-year OS rates, which were 98.4 percent, 93.5 percent, 91.9 percent and 91.9 percent in the SR group, and 91.9 percent, 82.3 percent, 74.1 percent and 74.1 percent in the RFA group, respectively (p<0.001).

Multivariate analysis of all patients showed that RFA was a significant predictor of poor PFS (hazard ratio [HR], 2.26; 95 percent CI, 1.52–3.35; p<0.001) and OS (HR, 2.25; 1.14–4.46; p=0.02).

Notably, the beneficial advantage of SR over RFA on OS was attenuated in patients with perivenous HCC (p=0.978), indicating that clinicians should take tumour location and type of peritumoural vessels into consideration when prescribing first-line treatments, said researchers.

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Most Read Articles
Roshini Claire Anthony, 5 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 09 Nov 2018
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
3 days ago
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.
Pearl Toh, 08 Nov 2018
The pneumonia-causing bacteria, Streptococcus pneumoniae (pneumococcus), can be spread through nose picking and rubbing after exposure of the hands to the bacteria — in addition to the conventionally known route of inhalation of airborne droplets, a study reveals.