Most Read Articles
Tristan Manalac, 30 Jan 2020
Despite being mostly sufficiently active, obese and overweight children with congenital heart disease (CHD) still need to increase physical activity levels, according to a recent study.
Pearl Toh, 6 days ago
Toddlers with a longer screen viewing time were more sedentary and spent less time engaged in physical activity later in life at age 5.5 years, according to the Growing Up in Singapore Towards healthy Outcomes (GUSTO) study — supporting the hypothesis that screen viewing may have a negative influence on health by displacing physical activity.
10 Feb 2020
Regardless of the type, disordered eating behaviours may lead to a higher body mass index (BMI) in the long run in adolescents, a recent study has shown.
Audrey Abella, 06 Feb 2020
Clinical hypnosis is an acceptable, feasible, and promising complementary therapy in adolescents with Crohn’s disease (CD), according to data presented at Crohn’s and Colitis 2020.

Suboptimal protein, energy intake contributes to severe PNGF in preterm VLBW infants

24 Nov 2019

About one-third of preterm infants with very low birthweight (VLBW) in Asia develop severe postnatal growth faltering (PNGF), with contributing factors including suboptimal protein and energy intake while in the neonatal intensive care unit, a study has found.

The study included 236 VLBW infants admitted to two hospitals in Singapore (n=108) and Malaysia (n=128) and survived to discharge over a 2-year follow-up. Of these, 74 had extremely low birth weight (ELBW).

Compared with infants from Malaysia, those from Singapore had lower intake of total protein (2.69 vs 3.54 g/kg/day; p<0.001) and energy (92.4 vs 128.9 kcal/kg/day; p<0.001) in enteral feeds. The latter were predominantly fed fortified breast milk (45/48 vs 10/41; p<0.01). There was a significant difference observed in mean weight z-score from birth to 36 weeks’ corrected age between Singaporean and Malaysian babies (–2.2 vs –1.4; p=0.001).

Severe PNGF (more than –2 SDS z-score) occurred with markedly greater frequency in the subgroup of Singaporean vs Malaysian ELBW infants (55 percent vs 16 percent; p=0.001). Researchers explained that this difference in incidence might be attributed to the higher use of a diuretic in Singapore to treat haemodynamically significant patent ductus arteriosus (hsPDA).

VLBW infants achieved a mean growth velocity of 15 g/kg/day from day 14. This was attained by ELBW infants only from day 28, in comparison. Severe PNGF rates (z-score change more than –2 SDS at 36 weeks' corrected age) were 28.8 percent for VLBW infants and 36.5 percent for ELBW infants.

The present data provide the opportunity to look at the differences in therapies that may influence growth outcomes in VLBW infants, as well as to improve nutritional support to at-risk infants, according to the researchers.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS JPOG - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Tristan Manalac, 30 Jan 2020
Despite being mostly sufficiently active, obese and overweight children with congenital heart disease (CHD) still need to increase physical activity levels, according to a recent study.
Pearl Toh, 6 days ago
Toddlers with a longer screen viewing time were more sedentary and spent less time engaged in physical activity later in life at age 5.5 years, according to the Growing Up in Singapore Towards healthy Outcomes (GUSTO) study — supporting the hypothesis that screen viewing may have a negative influence on health by displacing physical activity.
10 Feb 2020
Regardless of the type, disordered eating behaviours may lead to a higher body mass index (BMI) in the long run in adolescents, a recent study has shown.
Audrey Abella, 06 Feb 2020
Clinical hypnosis is an acceptable, feasible, and promising complementary therapy in adolescents with Crohn’s disease (CD), according to data presented at Crohn’s and Colitis 2020.