Most Read Articles
Audrey Abella, 07 Apr 2021
A novel oral testosterone replacement therapy (TRT*) formulation – testosterone undecanoate (TU) – showed favourable safety and efficacy as long-term treatment for men with low testosterone levels, according to the extension phase results of a study presented at ENDO 2021.
Natalia Reoutova, 08 Apr 2021

A randomized clinical trial (RCT) in 216 patients with painful diabetic neuropathy (PDN) refractory to 1 year of treatment with gabapentinoids and 1 other analgesic class shows that high-frequency (10 kHz) spinal cord stimulation (SCS) plus conventional medical management (CMM) is superior to CMM alone in terms of pain relief and health-related quality of life (HRQoL).

Roshini Claire Anthony, 2 days ago

In patients hospitalized with COVID-19, hypernatraemia during hospitalization may increase mortality risk, while hyponatraemia at admission may up the need for ventilation support, a recent study from the UK showed.

Stuttering teens at higher risk of early-onset T2D

08 Apr 2021

An association has been observed between stuttering in adolescence and an increased risk for early-onset type 2 diabetes (T2D) among men, reports a study.

A total of 2,193,855 adolescents aged 16–20 years who were assessed for military service between 1980 and 2013 were included in this nationwide population-based study. A speech-language pathologist confirmed the diagnosis of stuttering in adolescence.

The investigators determined T2D status for each participant as of 31 December 2016 using linkage to the Israeli National Diabetes Registry and analysed associations using regression models adjusted for socioeconomic variables, cognitive performance, coexisting morbidities, and adolescent body mass index. Analysis was stratified by sex (pinteraction=0.035).

T2D developed in 3.7 percent (n=162) of 4,443 adolescent men with stuttering, which was higher than the 2.1 percent in 25,678 men without stuttering (adjusted odds ratio [aOR], 1.3, 95 percent confidence interval [CI], 1.1–1.6).

The association stayed even when unaffected brothers of men with stuttering were used as reference (aOR, 1.5, 95 percent CI, 1.01–2.2) or when the analysis included only those with unimpaired health at baseline (aOR, 1.4, 95 percent CI, 1.1–1.7). Of note, this association was more pronounced in later birth cohorts, with an aOR of 1.4 (95 percent CI, 1.4–4.1) for cases of T2D before the age of 40 years.

In 503 adolescent women with stuttering, only 1.4 percent (n=7) developed T2D, slightly higher than the 1.1 percent in 10,139 women without stuttering (OR, 2.03, 95 percent CI, 0.48–2.20).

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Most Read Articles
Audrey Abella, 07 Apr 2021
A novel oral testosterone replacement therapy (TRT*) formulation – testosterone undecanoate (TU) – showed favourable safety and efficacy as long-term treatment for men with low testosterone levels, according to the extension phase results of a study presented at ENDO 2021.
Natalia Reoutova, 08 Apr 2021

A randomized clinical trial (RCT) in 216 patients with painful diabetic neuropathy (PDN) refractory to 1 year of treatment with gabapentinoids and 1 other analgesic class shows that high-frequency (10 kHz) spinal cord stimulation (SCS) plus conventional medical management (CMM) is superior to CMM alone in terms of pain relief and health-related quality of life (HRQoL).

Roshini Claire Anthony, 2 days ago

In patients hospitalized with COVID-19, hypernatraemia during hospitalization may increase mortality risk, while hyponatraemia at admission may up the need for ventilation support, a recent study from the UK showed.