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Stressful life events during pregnancy may promote rapid infant weight gain

09 Jul 2020

Maternal stress during pregnancy correlates with rapid weight gain of her infant, a recent study has found.

The study included 144 mother-child dyads. Maternal stress during pregnancy was categorized as objective (the number of stressful life events) or subjective (perceived stress and depressive symptoms). Rapid weight gain from birth to 6 months of age was assessed through birth records.  

Unadjusted binary logistic regression models showed that enduring stressful life events during pregnancy increased the risk of the child rapidly gaining weight during early life (odds ratio [OR], 1.42, 95 percent confidence interval [CI], 1.15–1.75; p=0.001).

This was not true for prenatal perceived stress (OR, 0.83, 95 percent CI, 0.48–1.44; p=0.50) or depressive symptoms (OR, 0.98, 95 percent CI, 0.90–1.08; p=0.71).

Adjusting for potential confounders did not meaningfully alter the primary findings. Prenatal stressful life events continued to associate with rapid infant weight gain, such that each additional event carried a 40-percent risk of the outcome (OR, 1.40, 95 percent CI, 1.07–1.83; p=0.014).

Similarly, perceived stress (OR, 0.47, 95 percent CI, 0.16–1.37; p=0.17) and depressive symptoms (OR, 0.89, 95 percent CI, 0.76–1.03; p=0.13) were unrelated to rapid infant weight gain. Adjusting for these subjective stress markers likewise did not attenuate the link between objective prenatal stress and infant weight gain.

“Current findings suggest that preventive interventions targeting exposure to prenatal stressful life events may help reduce risk for rapid infant weight gain,” researchers said.

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Most Read Articles
Elaine Soliven, 4 days ago

Switching from efavirenz/emtricitabine/tenofovir disoproxil fumarate (EFV/FTC/TDF) to the new bictegravir/ emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) regimen maintained high rates of virological suppression in adults who are living with HIV*, according to a study presented at AIDS 2020.

01 Aug 2020
Supplementation with probiotics may have positive effects in patients with type 2 diabetes mellitus (T2DM), reports a recent meta-analysis.
Stephen Padilla, 4 days ago
Pre-exposure prophylaxis (PrEP) containing either long-acting injectable cabotegravir (CAB) or tenofovir/emtricitabine (TDF/FTC) is safe and effective for transgender women (TGW) and cisgender men who have sex with men (MSM), but CAB results in a much lower HIV incidence compared to TDF/FTC, results of the HIV Prevention Trials Network (HPTN) 083 have shown.
Jairia Dela Cruz, 3 days ago
Monthly prophylaxis with the fixed-dose combination of naphthoquine-azithromycin (NQAZ) is well tolerated and confers significant protection against infection with Plasmodium parasites among individuals residing in malaria-endemic areas in Southeast Asia, as shown in the results of a phase III trial.