Most Read Articles
Stephen Padilla, 25 Jul 2019
Nonvitamin K antagonist oral anticoagulants (NOACs) appear to confer more clinical benefits to elderly patients with atrial fibrillation (AF) than vitamin K antagonist anticoagulants (VKAs), suggests a study, adding that this is primarily driven by the lower rates of major bleeding.
Rachel Soon, 05 Dec 2018

At the recent Malaysian Community Pharmacy Business Forum (MyCPBF), a discussion forum was held on the subject of “Transcending Primary Healthcare Services: The Future of Specialized Pharmacy Services and Pharmacy Specialization”.

12 Dec 2016

Associate Professor Ng Lee Ching, Director of the Environmental Health Institute (EHI) at the National Environment Agency (NEA), Singapore, speaks about the role of primary care physicians and government agencies in preventing dengue epidemics.

22 Aug 2018
In patients with atrial fibrillation (AF) naïve to oral anticoagulants (OACs), standard-dose nonvitamin K antagonist OACs (NOACs) provides better survival benefits than warfarin, a recent meta-analysis has shown.

Steroids, NSAIDs after laser trabeculoplasty reduce IOP

28 Oct 2019
Remind customers to use eye treatments for a month only, as, after that, they become ineffective

Eyes treated with steroid or nonsteroidal anti-inflammatory drug (NSAID) drops after selective laser trabeculoplasty (SLT) show significantly better reduction in intraocular pressure (IOP) at 12 weeks, a study has shown.

Patients aged >18 years with IOP of >18 mm Hg for whom the clinician decided SLT was the appropriate therapy were included in this double-masked, randomized, placebo-controlled, dual-centre, multisurgeon trial. They were randomly allocated to one of three groups: ketorolac 0.5%, prednisolone 1% or saline tears.

Participants were instructed to use an unmarked drop 4 times daily starting the day of SLT and continuing for 4 more days. The investigators used the Kruskal-Wallis test and Wilcoxon rank-sum test for continuous variables when comparing two or three treatment groups, respectively.  For categorical variables, the Fisher exact test was used.

Ninety-six eyes of 85 patients were included in the trial. All three groups had similar baseline demographics and baseline IOP (mean, 23.3±3.9 mm Hg; p=0.57).

At week 6, no statistically significant difference in IOP decrease was observed among the NSAID, steroid and placebo groups. At week 12, a statistically greater decrease in IOP was found in the NSAID and steroid groups compared with the placebo group (mean, –6.2±3.1 mm Hg, –5.2±2.7 mm Hg and –3±4.3 mm Hg, respectively; NSAID vs placebo: p=0.02 [analysis of variance] and p=0.002 [t test]; steroid vs placebo: p=0.02).

“Short-term postoperative use of NSAID or steroid drops may improve IOP reduction after SLT,” the investigators said. “Longer-term follow-up studies are indicated.”

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Most Read Articles
Stephen Padilla, 25 Jul 2019
Nonvitamin K antagonist oral anticoagulants (NOACs) appear to confer more clinical benefits to elderly patients with atrial fibrillation (AF) than vitamin K antagonist anticoagulants (VKAs), suggests a study, adding that this is primarily driven by the lower rates of major bleeding.
Rachel Soon, 05 Dec 2018

At the recent Malaysian Community Pharmacy Business Forum (MyCPBF), a discussion forum was held on the subject of “Transcending Primary Healthcare Services: The Future of Specialized Pharmacy Services and Pharmacy Specialization”.

12 Dec 2016

Associate Professor Ng Lee Ching, Director of the Environmental Health Institute (EHI) at the National Environment Agency (NEA), Singapore, speaks about the role of primary care physicians and government agencies in preventing dengue epidemics.

22 Aug 2018
In patients with atrial fibrillation (AF) naïve to oral anticoagulants (OACs), standard-dose nonvitamin K antagonist OACs (NOACs) provides better survival benefits than warfarin, a recent meta-analysis has shown.