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Staphylococcus aureus linked to food allergies

15 Aug 2019

Staphylococcus aureus infection is associated with food sensitization and allergy independently of eczema severity, a recent study has shown.

Drawing from the Learning Early About Peanut Allergy study (n=640), researchers determined that almost half (48.8 percent) of the participants had some form of S aureus colonization on at least one study visit. Levels of specific immunoglobulin E (sIgE) were used to assess sensitization to common food allergens, while eczema severity was clinically evaluated by a paediatric allergy expert.

There was a significant correlation between the production of sIgE and testing positive for S aureus at any point from baseline to 60 months. For instance, high levels of sIgE to hen’s egg white and peanuts was associated with positive skin S aureus at any time point.

Multivariate logistic regression models further showed that participants who had skin and/or nasal S aureus colonization were significantly more likely to have persistent egg allergy than those who did not have the bacteria (odds ratio [OR], 1.57, 95 percent CI, 1.02–2.42; p=0.042). This effect was stronger for nasal (OR, 1.61, 1.03–2.52; p=0.036) than skin (OR, 1.39, 0.88–2.19; p=0.160) colonization.

The role of S aureus was stronger for peanut sensitization, both for skin (OR, 2.94, 1.11–7.76; p=0.029) and nasal (OR, 2.41, 1.04–5.59; p=0.04) colonization. All risk analyses were corrected for the severity of eczema at 60 and 72 months.

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Most Read Articles
5 days ago
Cardiac biomarkers are useful for identifying community-acquired pneumonia (CAP) patients with an elevated risk of early and long-term cardiovascular (CV) events, according to a study.
3 days ago
Tofogliflozin is safe and effective for elderly patients with type 2 diabetes mellitus (T2DM), regardless of insulin and oral antidiabetic drugs, reports a new Japan study.
17 Aug 2019
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