Most Read Articles
3 days ago
A recent study has shown no improvement in the rate of blood pressure (BP) control despite an increase in the prevalence of antihypertensive medication use.
Roshini Claire Anthony, 11 Feb 2020

The consumption of processed meat or unprocessed red meat may be associated with a slightly elevated risk of incident cardiovascular disease (CVD)* and all-cause mortality, according to a US study.

29 Jan 2020
Several high-density lipoprotein (HDL) functionality parameters, which are linked to HDL roles on cholesterol metabolism, endothelial protection and antioxidant/anti-inflammatory defence, contribute to an increased risk of incident acute coronary syndromes and its manifestations in individuals at high risk of cardiovascular disease, a study reports.
Jairia Dela Cruz, 25 Nov 2019
Use of the PCSK9* inhibitor alirocumab in acute coronary syndrome (ACS) patients on a background of high-intensity statin treatment delivers reductions in total hospitalizations and death with corresponding gains in days alive and out of hospital (DAOH), according to the results of prespecified and posthoc analyses of the ODYSSEY OUTCOMES** trial presented at the American Heart Association (AHA) 2019 Scientific Sessions.

ST-segment depression ups risk of sudden cardiac death

14 Feb 2020
Electrocardiograms (ECG) still remains to be the gold standard in detecting heart diseases – one of the hurdles that the Apple Watch will have to overcome

In middle-aged adults, resting painless ST-segment depression (STD) appears to correlate with sudden cardiac death (SCD), a recent study has found.

Researchers enrolled 14,935 middle-aged adults (45.36 percent male) who had no prior history of coronary heart disease. STD was assessed using 12-lead electrocardiograms, and SCD was defined as unexpected arrest of cardiac origin, occurring within 24 hours of any symptoms.

Over a mean follow-up of 20.4±5.5 years, a total of 626 SCD events occurred, with a corresponding incidence rate of 1.1 per 1,000 person-years. Those with STD 0.05 mV at rest were significantly more likely to develop this outcome (adjusted hazard ratio [HR], 1.45, 95 percent confidence interval [CI], 1.20–1.76).

This effect was even stronger for those with painless STD 0.1 mV at rest (adjusted HR, 1.90, 95 percent CI, 1.25–2.88).

Notably, cumulative hazard curves showed increasing divergence over time. At study end, the absolute annual rate of SCD was 154.2 cases per 100,000 person-years in those with STD, substantially lower than the rate of 2,221.9 cases per 100,000 person-years in those with the condition. This represented an absolute jump in risk of 2,067.7 cases per 100,000 person-years.

Moreover, comorbidities seemed to influence the ties between STD and SCD. For instance, the correlation was only significant in those with hypertension (adjusted HR, 1.53, 95 percent CI, 1.13–2.07) but not in those without (adjusted HR, 1.21, 95 percent CI, 0.94–2.07). The association was also stronger in those without vs with diabetes mellitus (adjusted HR, 1.67 vs 1.03; pinteraction=0.005).

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Most Read Articles
3 days ago
A recent study has shown no improvement in the rate of blood pressure (BP) control despite an increase in the prevalence of antihypertensive medication use.
Roshini Claire Anthony, 11 Feb 2020

The consumption of processed meat or unprocessed red meat may be associated with a slightly elevated risk of incident cardiovascular disease (CVD)* and all-cause mortality, according to a US study.

29 Jan 2020
Several high-density lipoprotein (HDL) functionality parameters, which are linked to HDL roles on cholesterol metabolism, endothelial protection and antioxidant/anti-inflammatory defence, contribute to an increased risk of incident acute coronary syndromes and its manifestations in individuals at high risk of cardiovascular disease, a study reports.
Jairia Dela Cruz, 25 Nov 2019
Use of the PCSK9* inhibitor alirocumab in acute coronary syndrome (ACS) patients on a background of high-intensity statin treatment delivers reductions in total hospitalizations and death with corresponding gains in days alive and out of hospital (DAOH), according to the results of prespecified and posthoc analyses of the ODYSSEY OUTCOMES** trial presented at the American Heart Association (AHA) 2019 Scientific Sessions.