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Elaine Soliven, 27 Sep 2017
A second dose of kisspeptin-54 improves oocyte yield in women at high risk of ovarian hyperstimulation syndrome (OHSS) during in vitro fertilization (IVF) treatment, according to a recent study.
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Pearl Toh spoke with Dr Teh Ming Ming, senior consultant at the Department of Endocrinology, Singapore General Hospital (SGH), on the major challenges of diagnosing and managing diabetes in primary care, in conjunction with the World Diabetes Day on 14 November. Awareness of the symptoms of diabetes is important, and patients should be empowered to manage their conditions.
Rachel Soon, 2 days ago

Pharmacists can and should utilize their positions within communities to provide access to an extended range of healthcare services, says an expert.

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SSRI use not associated with cataract risk

30 Oct 2017

Use of selective serotonin reuptake inhibitors (SSRIs) does not appear to increase the risk of cataract, reports a recent study.

Researchers identified a total of 206,931 cataract cases matched with the same number of controls. There was no association between current long-term use of SSRI (≥20 prescriptions) and an increased cataract risk (adjusted odds ratio [aOR], 0.99; 95 percent CI, 0.94 to 1.03). On the other hand, a slightly increased risk of cataract was seen for long-term SSRI users compared with nonusers in a subgroup of patients aged 40 to 64 years.

“The slightly increased OR for individuals younger than 65 years of age in association with long-term SSRI use needs to be investigated in further studies,” researchers said.

In this case-control study, the authors derived the participants from the UK-based Clinical Practice Research Datalink (CPRD). Included were patients with first-time cataract aged ≥40 years between 1995 and 2015 and an equal number of cataract-free controls matched on age, sex, general practice, date of cataract recording (ie, index date) and years of history in the CPRD before the index date.

Conditional logistic regression analyses were conducted, adjusting for body mass index, smoking, hypertension, diabetes and systemic steroid use. The number of SSRI prescriptions and prescriptions for other antidepressant drugs were the exposure of interest. Mutually exclusive use of single SSRI substances was explored.

The index data was shifted backwards by 2 years in sensitivity analyses. Also, analyses were restricted to cases and controls without a prior glaucoma diagnosis.

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Most Read Articles
Elaine Soliven, 27 Sep 2017
A second dose of kisspeptin-54 improves oocyte yield in women at high risk of ovarian hyperstimulation syndrome (OHSS) during in vitro fertilization (IVF) treatment, according to a recent study.
23 Oct 2017
Pearl Toh spoke with Dr Teh Ming Ming, senior consultant at the Department of Endocrinology, Singapore General Hospital (SGH), on the major challenges of diagnosing and managing diabetes in primary care, in conjunction with the World Diabetes Day on 14 November. Awareness of the symptoms of diabetes is important, and patients should be empowered to manage their conditions.
Rachel Soon, 2 days ago

Pharmacists can and should utilize their positions within communities to provide access to an extended range of healthcare services, says an expert.

01 Aug 2017
New drug applications approved by US FDA as of 1 - 15 June 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.