Most Read Articles
Dr. Joseph Delano Fule Robles, 14 Nov 2017

A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated. 

14 Nov 2017
The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.
6 days ago
Both hatha yoga and a low-FODMAP (Fermentable, Oligo-, Di-, Monosaccharides and Polyol) diet can alleviate gastrointestinal symptoms, as well as improve a range of other psychological and physiological health parameters, in patients with irritable bowel syndrome (IBS), a study has shown.
6 days ago
Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.

Split-dose PEG for colonoscopy insufficient for bowel preparation in diabetic patients

26 Feb 2017

Preparation quality for colonoscopy is worse in individuals with diabetes than those without, a recent study has found. In addition, diabetic patients also experience longer cecal intubation and total procedure time.

A single-centre, prospective, investigator-blinded study was conducted to compare the efficacy and tolerability of split-dose polyethylene glycol (PEG) for diabetic vs nondiabetic patients. A total of 50 diabetic and 55 nondiabetic patients ingested 2 L PEG solution on the day before the procedure and another 2 L of the solution on the day of colonoscopy.

Researchers graded the quality of bowel preparation using the Ottawa scale.

A significant difference was seen in bowel preparation quality. Diabetic patients had a worse preparation except for mid colon compared with nondiabetic patients (total score 7.06 vs 5.54; p<0.001; right colon 2.28 vs 1.81; p<0.001; mid colon 1.70 vs 1.56; p=0.253; rectosigmoid colon 1.70 vs 1.14; p<0.001; fluid volume 1.38 vs 1.01; p=0.001).

Adequate preparation was achieved in about 70 percent of nondiabetic patients vs only 40 percent of diabetic patients (p=0.003), which also had longer cecal intubation time (6.4 vs 4.5; p=0.002) and total procedure time (22.1 vs 18.1; p=0.015).

There was no significant between-group difference in compliance and adverse events. In the diabetic group, a significant association was observed between inadequate bowel preparation and higher fasting plasma glucose (136 vs 121.8 mg/dL; p=0.016).

The results indicate that split-dose PEG preparation regimen is not adequate for optimal bowel preparation in diabetic patients undergoing colonoscopy, according to researchers.

Split-dose PEG is considered a standard bowel preparation regimen for colonoscopy in the general population, they added.

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Most Read Articles
Dr. Joseph Delano Fule Robles, 14 Nov 2017

A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated. 

14 Nov 2017
The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.
6 days ago
Both hatha yoga and a low-FODMAP (Fermentable, Oligo-, Di-, Monosaccharides and Polyol) diet can alleviate gastrointestinal symptoms, as well as improve a range of other psychological and physiological health parameters, in patients with irritable bowel syndrome (IBS), a study has shown.
6 days ago
Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.