Most Read Articles
Pearl Toh, 2 days ago
First-line therapy with the BTK* inhibitor ibrutinib plus the anti-CD20 immunotherapy rituximab confers significant survival advantage over the current gold-standard regimen of fludarabine, cyclophosphamide, and rituximab (FCR) for young, fit patients with treatment-naïve chronic lymphocytic leukaemia (CLL), according to the E1912 trial, a large cooperative group study supported by the US National Cancer Institute.
6 days ago
Percutaneous coronary intervention (PCI) displays comparable rates of mortality and serious composite outcomes but a higher rate of target-vessel revascularization at 10 years relative to coronary artery bypass grafting (CABG) in patients with significant left main coronary artery (LMCA) disease, reports a study. On the other hand, CABG delivers lower mortality and serious composite outcome rates compared with PCI with drug-eluting stents after 5 years.
Pearl Toh, 07 Dec 2018
Apixaban slashes the risk of recurrent venous thromboembolism (VTE) by 90 percent in cancer patients compared with the low-molecular-weight heparin (LMWH) dalteparin, with no increase in major bleeding risk, according to the ADAM VTE study presented at ASH 2018.
2 days ago
Rates of major bleeding events are similar across cancer patients taking direct oral anticoagulants (DOAC), low-molecular-weight heparin (LMWH) or vitamin K antagonist (VKA), with gastrointestinal bleeding being the most frequent event, a recent study has shown. In addition, DOAC and LMWH recorded higher rates of venous thromboembolism than earlier studies.

Specific symptomatological, cognitive profile overlaps between schizophrenia, ASD

13 Apr 2018

There appears to be a subgroup of schizophrenic patients who exhibit autism spectrum disorder (ASD) features characterized by specific symptomatological and cognitive profile, a study has found.

A total of 75 patients with schizophrenia (mean age 42 years; 26.67 percent female) underwent the Autism Diagnostic Observation Schedule (ADOS) and the Autism Diagnostic Interview-Revised (ADI-R) assessments. Clinical, neuropsychological and psychosocial functioning were also measured.

Of the patients, 47 were negative to all the autism scales administered (ADOS-TOT-NEG), 21 were positive to the ADOS Language subdomain (ADOS-L-POS), 21 were positive to the ADOS Reciprocal Social Interaction (RSI) subdomain (ADOS-RSI-POS), 14 were positive to the ADOS Total scale (ADOS-TOT-POS), and nine were positive to the ADI-R scale (ADI-R-POS).

Schizophrenic patients with and without ASD traits differed in terms of demographic (duration of illness), psychopathological (negative symptoms and general psychopathology) and cognitive (working memory and processing speed) functioning. There were no differences observed in psychosocial functioning.

While schizophrenia and ASD are two distinct behavioural outcomes of aberrant neurodevelopment, their overlapping characteristics and potential co-occurrence might pose substantial diagnostic challenges in clinical practice, researchers pointed out. Undiagnosed co-occurring disorders may lead to individuals not receiving appropriate services benefits or treatment.

The present data may thus contribute to better characterize patients with schizophrenia and subsequently develop new procedures and therapeutic tools in a more personalized perspective, researchers said.

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Most Read Articles
Pearl Toh, 2 days ago
First-line therapy with the BTK* inhibitor ibrutinib plus the anti-CD20 immunotherapy rituximab confers significant survival advantage over the current gold-standard regimen of fludarabine, cyclophosphamide, and rituximab (FCR) for young, fit patients with treatment-naïve chronic lymphocytic leukaemia (CLL), according to the E1912 trial, a large cooperative group study supported by the US National Cancer Institute.
6 days ago
Percutaneous coronary intervention (PCI) displays comparable rates of mortality and serious composite outcomes but a higher rate of target-vessel revascularization at 10 years relative to coronary artery bypass grafting (CABG) in patients with significant left main coronary artery (LMCA) disease, reports a study. On the other hand, CABG delivers lower mortality and serious composite outcome rates compared with PCI with drug-eluting stents after 5 years.
Pearl Toh, 07 Dec 2018
Apixaban slashes the risk of recurrent venous thromboembolism (VTE) by 90 percent in cancer patients compared with the low-molecular-weight heparin (LMWH) dalteparin, with no increase in major bleeding risk, according to the ADAM VTE study presented at ASH 2018.
2 days ago
Rates of major bleeding events are similar across cancer patients taking direct oral anticoagulants (DOAC), low-molecular-weight heparin (LMWH) or vitamin K antagonist (VKA), with gastrointestinal bleeding being the most frequent event, a recent study has shown. In addition, DOAC and LMWH recorded higher rates of venous thromboembolism than earlier studies.