Most Read Articles
Stephen Padilla, 4 days ago
Diabetic patients in a decompensated state and who develop type 2 myocardial infarction (MI) have an increased risk for mortality and major adverse cardiac events (MACE), according to a new study. In addition, these patients are potentially at risk for undiagnosed coronary artery disease.
6 days ago
Chocolate consumption is not associated with risk of coronary heart disease (CHD), stroke or both combined in postmenopausal women free of pre-existing major chronic disease, a study suggests.
Pearl Toh, 13 Jul 2018
More intensive lowering of LDL-C levels was associated with a progressively greater survival benefit than less intensive approach, when the baseline LDL-C levels were ≥100 mg/dL, reveals a meta-analysis of 34 randomized trials.
6 days ago
Switching from thiazide diuretic to ipragliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, leads to improvements in metabolic parameters and body mass composition without affecting blood pressure in type 2 diabetes (T2D) patients, a recent study has found.

Specific symptomatological, cognitive profile overlaps between schizophrenia, ASD

13 Apr 2018

There appears to be a subgroup of schizophrenic patients who exhibit autism spectrum disorder (ASD) features characterized by specific symptomatological and cognitive profile, a study has found.

A total of 75 patients with schizophrenia (mean age 42 years; 26.67 percent female) underwent the Autism Diagnostic Observation Schedule (ADOS) and the Autism Diagnostic Interview-Revised (ADI-R) assessments. Clinical, neuropsychological and psychosocial functioning were also measured.

Of the patients, 47 were negative to all the autism scales administered (ADOS-TOT-NEG), 21 were positive to the ADOS Language subdomain (ADOS-L-POS), 21 were positive to the ADOS Reciprocal Social Interaction (RSI) subdomain (ADOS-RSI-POS), 14 were positive to the ADOS Total scale (ADOS-TOT-POS), and nine were positive to the ADI-R scale (ADI-R-POS).

Schizophrenic patients with and without ASD traits differed in terms of demographic (duration of illness), psychopathological (negative symptoms and general psychopathology) and cognitive (working memory and processing speed) functioning. There were no differences observed in psychosocial functioning.

While schizophrenia and ASD are two distinct behavioural outcomes of aberrant neurodevelopment, their overlapping characteristics and potential co-occurrence might pose substantial diagnostic challenges in clinical practice, researchers pointed out. Undiagnosed co-occurring disorders may lead to individuals not receiving appropriate services benefits or treatment.

The present data may thus contribute to better characterize patients with schizophrenia and subsequently develop new procedures and therapeutic tools in a more personalized perspective, researchers said.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Stephen Padilla, 4 days ago
Diabetic patients in a decompensated state and who develop type 2 myocardial infarction (MI) have an increased risk for mortality and major adverse cardiac events (MACE), according to a new study. In addition, these patients are potentially at risk for undiagnosed coronary artery disease.
6 days ago
Chocolate consumption is not associated with risk of coronary heart disease (CHD), stroke or both combined in postmenopausal women free of pre-existing major chronic disease, a study suggests.
Pearl Toh, 13 Jul 2018
More intensive lowering of LDL-C levels was associated with a progressively greater survival benefit than less intensive approach, when the baseline LDL-C levels were ≥100 mg/dL, reveals a meta-analysis of 34 randomized trials.
6 days ago
Switching from thiazide diuretic to ipragliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, leads to improvements in metabolic parameters and body mass composition without affecting blood pressure in type 2 diabetes (T2D) patients, a recent study has found.