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Soft drinks play role in asthma development

3 days ago

Drinking soft drinks may be linked to asthma in adults and wheeze in children, according to a meta-analysis. Furthermore, prenatal maternal consumption of the drink can promote the development of inflammatory disease of the airways of the lungs in the offspring.

Researchers searched multiple online databases for studies examining the association between soft drinks consumption (including maternal consumption during pregnancy) and asthma or wheeze. A total of 19 studies were included in the systematic review and 18 in the meta-analyses.

Of the studies included (three cohort and 16 cross-sectional studies), 12 reported on childhood exposure to soft drinks, six on adulthood exposure and two on maternal consumption. Six studies were conducted in Europe, six in the USA, four in Asia, and one each in Brazil, New Zealand and Australia. There were 468,836 participants in total—among whom 236,932 were children, 170,385 were adults and 61,519 were pregnant women—with >50,000 cases of asthma.

Pooled data showed that soft drinks consumption was associated with an increased likelihood of asthma in both adults (odds ratio [OR], 1.37, 95 percent confidence interval [CI], 1.23–1.52) and children (OR, 1.14, 95 percent CI, 1.06–1.21).

Moreover, prenatal exposure showed a marginal association with asthma in children (OR, 1.11, 95 percent CI, 1.00–1.23).

In a subgroup analysis evaluating childhood exposure, the association with asthma persisted for sugar-sweetened soft drinks but not for carbonated drinks.

The findings underscore a need for additional longitudinal research to shed light on the relationship between soft drinks and asthma and mechanisms of action. The researchers called for continued initiation and support of measures to cut the consumption of soft drinks, especially given the other health effect associated with soft drinks, including obesity and dental caries.

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Most Read Articles
05 Nov 2019
Low total cholesterol levels appear to carry increased major adverse cardiovascular events (MACE) hazard in older men without ischaemic heart disease (IHD) and not receiving statin therapy but not to those on statins, according to data from the CHAMP (Concord Health and Ageing in Men Project) cohort.
Yesterday
Better sleep appears to weaken pain and fatigue in older, community-dwelling adults with hip or knee osteoarthritis (OA), reports a recent study.
5 days ago
Maribavir 400 mg twice daily appears to have comparable efficacy to valganciclovir at clearing cytomegalovirus viraemia in transplant recipients, a study has found.
4 days ago
Individuals with and without gout appear to have a similar risk of developing colorectal cancer, suggesting that gout does not contribute to a risk increase, a study has found.