Smoking cessation improves survival in diabetics
Quitting smoking following diabetes diagnosis appears to significantly cut mortality risk, particularly when paired with proper weight management, a recent Korea study has shown.
Researchers recruited 17,204 males (median age 52 years) who were newly diagnosed with type 2 diabetes and free from stroke or myocardial infarction. Survival regression analysis was performed to determine the risk of all-cause and cardiovascular diseases.
Multivariate adjusted analysis showed that men who quit smoking but showed no changes in body mass index (BMI) had a significantly lower risk of all-cause mortality compared with sustained smokers (adjusted hazard ratio [HR], 0.68; 95 percent CI, 0.46–1.00; p=0.05).
Men who quit smoking but gained BMI also showed a reduced risk of all-cause mortality, but the effect was not statistically significant (adjusted HR, 0.67; 0.36–1.24; p=0.21). Interestingly, smoking cessation coupled with BMI loss resulted in a significant increase in the risk of mortality (adjusted HR, 1.76; 1.13–2.73; p=0.01).
None of the patient groups were associated with significant changes in the risk of cardiovascular diseases. However, smoking cessation with BMI loss was associated with a nominal increase in the risk (adjusted HR, 1.09; 0.71–1.68; p=0.71), while cessation with BMI gain led to a marginal drop in the risk (adjusted HR, 0.94; 0.60–1.47; p=0.79).
The findings of the present study suggest that physicians should inform newly-diagnosed type 2 diabetes patients about the potential survival benefits of smoking cessation, as well weight management strategies that may help maximize the said benefits, according to researchers.