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Smoking, but not alcohol, ups risk of psoriasis

11 Mar 2019
The Health Ministry plans to raise the minimum age limit for smoking to 21 years.

The risk of psoriasis is higher among current smokers, particularly those who smoke >25 cigarettes per day and for >20 pack-years, according to a Taiwanese population-based cohort study. On the other hand, alcohol consumption shows no significant association with psoriasis development.

Psoriasis developed in 242 (0.40 percent) of 60,136 participants. After controlling for demographics and comorbidities, no significant association was found between alcohol consumption and risk of psoriasis.

In contrast, there was a higher risk of psoriasis for current smokers compared with never smokers (adjusted hazard ratio, 1.47; 95 percent CI, 1.04–2.07). This risk was particularly augmented among individuals who smoked >25 cigarettes per day and for >20 pack-years. Furthermore, subgroup analysis revealed that current smoking significantly correlated with psoriasis risk without psoriatic arthritis but not psoriatic arthritis alone.

To examine the effects of alcohol and smoking on incident psoriasis, the authors collected alcohol consumption, smoking status and other covariates from four rounds (2001, 2005, 2009 and 2013) of the Taiwan National Health Interview Survey. They identified incident psoriasis from the National Health Insurance database. Analysis was conducted using the Cox regression model.

This study was limited by the failure to assess alcohol consumption based on the number of drinks consumed.

“Alcohol consumption and smoking have long been suspected of increasing the risk of developing psoriasis. Most evidence to date has derived from cross-sectional or case-control studies,” the authors noted.

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Most Read Articles
5 days ago

Dr Michael Lim, a senior consultant at the Paediatric Pulmonary and Sleep Division, National University Hospital, Singapore, speaks to Roshini Claire Anthony on the rare disease that is cystic fibrosis.

3 days ago
Susceptibility‐guided therapy is as effective as empiric modified bismuth quadruple therapy for the first-line treatment of Helicobacter pylori infection, with both yielding excellent eradication rates, as shown in a recent trial.
5 days ago
It appears that long-term consumption of fish and omega-3 fatty acid does not influence the risk of incident hypertension in middle-aged and older men, suggests a US study.
3 days ago
The risk factors and outcomes associated with an increased risk of permanent pacing include atrial fibrillation (AF) ablation, multivalve surgery and New York Heart Association (NYHA) functional class III/IV, a recent study has found.