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Tristan Manalac, 6 days ago
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Sleep-disordered breathing a red flag for ischaemic stroke recurrence

15 Mar 2019

Sleep-disordered breathing (SDB) is associated with an increased risk of recurrent ischaemic stroke but not mortality, a study has shown.

The study included 842 ischaemic stroke patients (median age, 65 years; 47 percent female) from the BASIC* project. All patients underwent screening for SDB (defined as respiratory event index [REI] score ≥10) with the ApneaLink Plus device, as well as active and passive surveillance for recurrent ischaemic stroke.

Results showed that the median REI score was 14 (interquartile range, 6–26), with more than half of the population (63 percent) having SDB. SDB was associated with male sex, Mexican American ethnicity, lower educational attainment, higher body mass index, nonsmoking status, diabetes mellitus and hypertension.

Among 775 Mexican American and non-Hispanic whites with an index stroke event and complete data, 85 (11 percent) recurrent ischaemic stroke events and 104 (13 percent) deaths occurred over a median follow-up of 591 days.

In fully adjusted cause-specific proportional hazards models, REI was associated with an increased risk of recurrent ischaemic stroke (1-unit higher REI score: hazard ratio [HR], 1.02; 95 percent CI, 1.01–1.03) but not with the risk of mortality alone (HR, 1.00; 0.99–1.02).

According to researchers, SDB could not explain the previously identified higher risk of recurrent stroke in Mexican Americans vs non-Hispanic whites. Nevertheless, the present data support the need for a trial of SDB treatment for recurrent stroke prevention regardless of ethnicity.

*Brain Attack Surveillance in Corpus Christ

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Most Read Articles
Tristan Manalac, 6 days ago
Left ventricular assist devices (LVADs) can reverse pulmonary hypertension secondary to left heart disease regardless of baseline pulmonary vascular resistance, according to a new study.
Yesterday
It appears that long-term consumption of fish and omega-3 fatty acid does not influence the risk of incident hypertension in middle-aged and older men, suggests a US study.
11 May 2019
Acute kidney injury (AKI) commonly occurs within a year after cancer diagnosis in paediatric patients and is tied to long-term deteriorations in renal function, a recent study has found.
11 May 2019
Women practicing exclusive breastfeeding for 6 months achieve greater postpartum weight loss compared with those exclusively breastfeeding for a shorter duration, according to data from the MILK* study.