Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Elvira Manzano, 4 days ago

The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.

Pearl Toh, 5 days ago
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.
14 Sep 2019
In type 2 diabetes patients taking sulfonylureas, hypoglycaemia duration is longer at night and is inversely correlated with the level of glycated haemoglobin (HbA1c), a new study reports.

Sleep deprivation in early childhood may promote ADHD in subsequent years

17 Mar 2019

Preschool-aged children who are not getting enough sleep at night are at increased risk of developing attention-deficit/hyperactivity disorder (ADHD) in middle childhood, a study has found.

Researchers enrolled 514 kindergarteners, among whom only 408 (mean age at preschool [K3], 5.52 years; 51.5 female) were available for reassessment at the 3-year follow-up when the children were in the third grade in primary school (P3; mean age, 9.35 years). Pertinent data were obtained from the parents and health records.

In K3, four children (1.0 percent) were diagnosed with obstructive sleep apnoea, 26 (6.4 percent) had persistent snoring and 20 (4.9 percent) received methylphenidate medication. Only 43 children (10.5 percent) were getting the recommended sleep duration of 11–12 hours per day.

In P3, 126 children (30.9 percent) had the recommended sleeping duration of ≥10 hours per day, 38 (9.3 percent) had regular sleep patterns and 176 (43.1 percent) had good sleep quality. Meanwhile, 61 children (15.0 percent) had probable ADHD, 70 (17.2 percent) had probable ADHD with predominantly inattentive symptoms and 66 (16.2 percent) had probable ADHD with predominantly hyperactive symptoms.

Adjusted Poisson regression models revealed a significant association between sleep duration in K3 and subsequent probable ADHD in P3. The resulting risk ratios vs children with 11–12 hours of sleep were 14.62 in those with <8 hours of sleep (p=0.02), 10.61 in those with 8 to <9 hours of sleep (p=0.02) and 9.29 in those with 9 to <11 hours of sleep (p=0.03). This association was robust to sensitivity analysis (p<0.001).

In light of the findings, researchers highlighted the potential of extending sleep education to parents and caregivers and alert them of the deleterious impact of early childhood sleep deprivation on long-term development. Paediatricians should also acknowledge the potential adverse effect of sleep deprivation on ADHD and provide appropriate treatment and advice for children with sleep problems.

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Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Elvira Manzano, 4 days ago

The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.

Pearl Toh, 5 days ago
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.
14 Sep 2019
In type 2 diabetes patients taking sulfonylureas, hypoglycaemia duration is longer at night and is inversely correlated with the level of glycated haemoglobin (HbA1c), a new study reports.