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Skipping breakfast before and during early pregnancy ups GDM risk

28 Apr 2020

Women who skip breakfast before and during early pregnancy have a higher risk of developing gestational diabetes mellitus (GDM) than those who have the essential meal daily, suggests a study.

Of the 84,669 pregnant women included in the analysis, 1,935 had GDM. Compared with daily breakfast eaters, women who consumed breakfast 5–6 times/week had a 9-percent higher risk of GDM (multivariable-adjusted odds ratio [aOR], 1.09, 95 percent confidence interval [CI], 0.93–1.27), while those who consumed breakfast 3–4 and 0–2 times/week had a 14-percent (aOR, 1.14, 95 percent CI, 0.96–1.34) and 21-percent (aOR, 1.21, 95 percent CI, 1.05–1.41) increased risk, respectively.

A dose-dependent association was observed (ptrend=0.006). Moreover, prepregnancy body mass index (BMI) significantly modified such association.

“Breakfast consumption <3 times/week before and during early pregnancy, compared with daily consumption, was associated with an increased odds of developing GDM,” the authors said.

During study enrolment from January 2011 to March 2014, the authors registered a total of 103,099 pregnancies, including 97,454 pregnant women from 15 areas across Japan. Eligibility criteria for participants was singleton pregnancy free of GDM, stroke, heart disease, cancer, and type 1 or type 2 diabetes at study enrolment.

A self-administered questionnaire was used to gather data on demographic information, socioeconomic status, self-rated health status, disease, history, lifestyle and dietary habits of each women at study enrolment. A semiquantitative food-frequency questionnaire was used for dietary assessment. Finally, the authors estimated the OR of GDM in relation to breakfast consumption using logistic regression.

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Most Read Articles
Pearl Toh, 22 Oct 2020
The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
Roshini Claire Anthony, 13 Nov 2020

Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.

Pearl Toh, 5 days ago
Inhaled corticosteroid (ICS) should be the mainstay of long-term asthma management — such is the key message of the latest Singapore ACE* Clinical Guidance (ACG) for asthma, released in October 2020.
Elvira Manzano, 17 Nov 2020
Invasive fungal infections, particularly those caused by Candida species, are common in hospitalized, immunocompromised, or critically ill patients and are associated with considerable morbidity and mortality.