Most Read Articles
19 Dec 2016
The prevalence of ECG for left ventricular hypertrophy (LVH) may vary depending on the criteria used across body mass index (BMI) categories in a low cardiovascular risk cohort, suggests a new study.
02 Dec 2017
The risk of congenital heart disease (CHD) Is significantly higher in foetuses conceived through in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI), according to a recent study.
Pearl Toh, 3 days ago
A higher dose of pitavastatin can benefit Japanese patients with stable coronary artery disease (CAD) compared with a low-dose pitavastatin, even though cardiovascular (CV) event incidence is known to be lower in Asian than Western patients, according to the REAL-CAD study presented at the AHA Scientific Sessions 2017.
01 Apr 2014
The basic life support (BLS) termination of resuscitation (TOR) rule recommends transport and continued resuscitation when cardiac arrest is witnessed by EMT-Ds, or there is a return of spontaneous circulation, or a shock is given.

Serum resistin predicts aortic stiffness in coronary artery disease

01 Sep 2017

Serum concentrations of resistin is a biomarker for aortic stiffness in patients with coronary artery disease (CAD), a recent study from Taiwan has shown.

The aortic stiffness of 104 CAD patients (mean age 65.63±9.17 years; 75 percent male) was measured using carotid-femoral pulse wave velocity. Those with acute myocardial infarction, pulmonary oedema, acute infections or were taking calcium, bisphosphonates or oestrogens were excluded.

Fasting blood samples were collected from the participants and were subjected to laboratory tests to measure levels of blood urea nitrogen (BUN), high- and low-density lipoprotein (HDL, LDL) and high-sensitivity C-reactive protein (hs-CRP).

Of the participants, 35.6 percent (n=37) had high aortic stiffness. Diabetes mellitus was more common in patients with high aortic stiffness (p=0.001).

Serum resistin levels were significantly higher in patients with both CAD and diabetes mellitus than in those without the diabetes comorbidity (p=0.003). Resistin levels were not significantly different with respect to the presence of the hypertension comorbidity.

Multivariate forward stepwise linear regression analysis showed that diabetes mellitus (β, 0.239; p=0.006), waist circumference (β, 0.384; p<0.001) and age (β, 0.203; p=0.019) were all significant predictors of resistin concentrations in CAD patients.

Subsequent multivariate logistic regression showed that higher serum resistin (odds ratio [OR], 1.275; 95 percent CI, 1.065 to 1.527; p=0.008), diabetes mellitus (OR, 4.906; 1.418 to 16.970; p=0.012), older age (OR, 1.089; 1.005 to 1.180; p=0.036) and higher hs-CRP (OR, 1.226; 1.010 to 1.486; p=0.039) were independent predictors of aortic stiffness in CAD patients.

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Most Read Articles
19 Dec 2016
The prevalence of ECG for left ventricular hypertrophy (LVH) may vary depending on the criteria used across body mass index (BMI) categories in a low cardiovascular risk cohort, suggests a new study.
02 Dec 2017
The risk of congenital heart disease (CHD) Is significantly higher in foetuses conceived through in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI), according to a recent study.
Pearl Toh, 3 days ago
A higher dose of pitavastatin can benefit Japanese patients with stable coronary artery disease (CAD) compared with a low-dose pitavastatin, even though cardiovascular (CV) event incidence is known to be lower in Asian than Western patients, according to the REAL-CAD study presented at the AHA Scientific Sessions 2017.
01 Apr 2014
The basic life support (BLS) termination of resuscitation (TOR) rule recommends transport and continued resuscitation when cardiac arrest is witnessed by EMT-Ds, or there is a return of spontaneous circulation, or a shock is given.