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Stephen Padilla, 21 Apr 2021
People who are physically active are less likely to progress to severe COVID-19 if diagnosed with the disease as opposed to their physically inactive counterparts, suggests a recent study.
Tristan Manalac, 18 Mar 2021
Both daily and on-demand regimens of pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine (TDF/FTC) strongly suppress the rates of HIV infection among men who have sex with men (MSM), according to a study presented at the 2021 Conference on Retroviruses and Opportunistic Infections (CROI 2021).
Stephen Padilla, 18 Mar 2021
Sex appears to have a strong influence on many discrete pathways of inflammation that independently predict cardiovascular disease (CVD) and venous thromboembolism (VTE) events in patients with HIV on antiretroviral therapy (ART), according to a study presented at the Conference on Retroviruses and Opportunistic Infections 2021.
02 May 2021
Vaccination against SARS-CoV-2 does not seem to come with significant safety concerns in patients with nonalcoholic fatty liver disease (NAFLD), a recent study has found. At the same time, vaccines can also elicit a robust neutralizing antibody response.

Septic arthritis of facet joint incidence in children higher than expected

6 days ago

Incidence of septic arthritis of the facet joint (SAFJ) in children is much higher than seen in literature, with half of the cases complicated by an epidural infection, reveals a study.

“Simple clinical symptoms detected as early as the bedside allow a strong suspicion of SAFJ, justifying the use of a first-line magnetic resonance imaging (MRI) to confirm the diagnosis and precisely describe the extension,” the authors said.

The study sought to estimate the incidence rate of SAFJ in children, specify SAFJ clinical, imaging, and laboratory findings, and identify avenues for appropriate management. The authors carried out a 10-year consecutive SAFJ case series using their imaging centre database combined with a 50-year systematic review of literature cases.

The mean incidence of paediatric SAFJ was 0.23±0.4 per 100,000 children-years. Key symptoms were as follows: potty refusal (in toddlers) or painful sitting (78 percent) and lateralized signs (paravertebral tenderness and/or swelling (88 percent). MRI was used to obtain SAFJ diagnosis and extension (94 percent); epidural extension was found in eight of 16 cases.

Antibiotic treatment lasted for a mean of 5.1 weeks. The compliance with guidelines was 79 percent for empiric and 62 percent for targeted antibiotic therapies.

“Focusing on simple clinical signs is key to justify the transfer of a child or the shortening of the delay to obtain an MRI,” the authors said. “However, as MRI availability increases in most Western countries, and the capacity for diagnosis increases, the awareness of SAFJ must be spread to avoid missed cases.”

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Most Read Articles
Stephen Padilla, 21 Apr 2021
People who are physically active are less likely to progress to severe COVID-19 if diagnosed with the disease as opposed to their physically inactive counterparts, suggests a recent study.
Tristan Manalac, 18 Mar 2021
Both daily and on-demand regimens of pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine (TDF/FTC) strongly suppress the rates of HIV infection among men who have sex with men (MSM), according to a study presented at the 2021 Conference on Retroviruses and Opportunistic Infections (CROI 2021).
Stephen Padilla, 18 Mar 2021
Sex appears to have a strong influence on many discrete pathways of inflammation that independently predict cardiovascular disease (CVD) and venous thromboembolism (VTE) events in patients with HIV on antiretroviral therapy (ART), according to a study presented at the Conference on Retroviruses and Opportunistic Infections 2021.
02 May 2021
Vaccination against SARS-CoV-2 does not seem to come with significant safety concerns in patients with nonalcoholic fatty liver disease (NAFLD), a recent study has found. At the same time, vaccines can also elicit a robust neutralizing antibody response.