Secondary bacterial infections common in patients with dermatitis
Chinese patients with dermatitis commonly suffer from secondary bacterial infections, a recent observational study has shown. Moreover, atopic dermatitis is a common dermatitis subtype.
In the study, 8,758 outpatients with eczema or dermatitis (mean age 33.99±years; 50.6 percent male) were screened for secondary bacterial infections based on the presence of pustules, yellow-coloured crusts or prudent exudation. Those with incomplete baseline information were excluded.
In the study population, the most common subtype of specified eczema was atopic dermatitis, which was observed in 13.4 percent (n=1,174). This was followed by irritant dermatitis (9.2 percent; n=810), widespread eczema (8.7 percent; n=765), hand eczema (6.7 percent; n=590) and allergic contact dermatitis (5.9 percent; n=513).
Those with unspecified eczema comprised 35.5 percent (n=3,109) of the study population.
In terms of having suspected secondary bacterial infection, the leading dermatitis subtype was atopic dermatitis, with 50.1 percent. This was followed by widespread eczema (47.3 percent) and asteatotic eczema (43.5 percent).
The total bacterial infection rate was significantly higher in males than in females (52.8 vs 48.3 percent). The rates of suspected (17.5 vs 15.6 percent) and very likely (35.3 vs 32.7 percent) infection rates were likewise higher in males (p<0.05, chi-square test).
Multivariable logistic regression analysis showed that age (odds ratio [OR[, 0.969; 95 percent CI, 0.961 to 0.977; p<0.001), disease duration (OR, 1.037; 1.023 to 1.051; p<0.001), severe itching (OR, 3.018; 2.056 to 4.429; p<0.001), history of dry skin (OR, 0.750; 0.637 to 0.881; p<0.001), history of flexion dermatitis (OR, 1.922; 1.591 to 2.322; p<0.001) and history of allergic disease (OR, 1.182; 1.001 to 1.396; p=0.049) were all independent risk variables for very likely bacterial infections.