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Sarcopenic obesity ups fall risk in postmenopausal women

16 Nov 2018

Sarcopenic obesity appears to increase the rate of falls in postmenopausal women, particularly in those of Hispanic background, reports a recent study.

Using dual-energy x-ray absorptiometry, researchers evaluated bone and body composition in 9,924 postmenopausal women (aged 50–79 years). Those with both sarcopenia (lowest 20th percentile of appendicular lean mass) and obesity (body fat percentage >42 percent) were determined to have sarcopenic obesity.

Majority (74.7 percent; n=7,415) of the sample were nonfallers reporting at most one fall event in any year. The remaining 25.3 percent (n=2,509) had at least two falls per year and were categorized as fallers.

Stratifying the participants according to age, researchers found that in those who were aged 50–64 years at baseline, all three measures of body composition were associated with higher risks of falls: sarcopenia (adjusted relative risk [RR], 1.32; 95 percent CI, 1.01–1.74), obesity (adjusted RR, 1.22; 1.08–1.37) and sarcopenic obesity (adjusted RR, 1.35; 1.17–1.56).

In comparison, in women aged 65–79 years at baseline, only obesity (adjusted RR, 1.16; 1.03–1.30) and sarcopenic obesity (adjusted RR, 1.21; 1.05–1.39), but not sarcopenia alone (adjusted RR, 1.07; 0.81–1.43), were significantly correlated with falls.

In terms of race and ethnicity, researchers showed that sarcopenic obesity strongly predicted fall incidence in Hispanic (adjusted RR, 2.40; 1.56–3.67) and non-Hispanic White (adjusted RR, 1.24; 1.11–1.39) participants.

Further studies should focus on coming up with age- and race-specific prevention strategies for sarcopenic obesity in postmenopausal women, researchers said.

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Most Read Articles
5 days ago
Living a sedentary lifestyle may increase the risk of cardiovascular diseases (CVD) even in people with healthy body mass index (BMI), reports a new study.
04 Feb 2019
The carbon-chain length of saturated fatty acids appears to be an important factor in determining its role in cardiovascular health, a recent study has found.
3 days ago
Olanzapine confers a modest therapeutic effect on weight compared with placebo in adult outpatients with anorexia nervosa, a study has shown. However, it does not appear to offer significant benefit for psychological symptoms.
Jairia Dela Cruz, 04 Feb 2019
Treatment with secukinumab results in a higher rate of remission or low-disease activity at week 16 in patients with psoriatic arthritis as compared with placebo, according to a posthoc analysis of the FUTURE 2 study. This effect is sustained at 2 years and is evident in both tumour necrosis factor inhibitor-experienced and -naïve patients.