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10 Jan 2018
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A new batch of apolipoprotein B (apoB)-lowering drugs that capitalize on statins’ ability to lower lipids will further benefit patients at high cardiovascular (CV) risk who need to be treated more aggressively.

Pearl Toh, 15 Dec 2017
Blood pressure (BP) readings appeared to be similar regardless of whether BP measurements were attended or unattended by staff, nor were CV outcomes different between the two techniques, according to a post hoc survey on participants following the SPRINT* trial.

Rotating shift work may increase risk of hypertension

25 Sep 2017

Shift work status appears to influence the development of hypertension, according to a recent study. Rotating shift work is more likely to increase the risk of high blood pressure, but no significant association exists between night shift status and hypertension.

In this systematic review and meta-analysis, researchers performed a literature search using Medline, Embase and Cochrane Database from inception through October 2016. Those included were articles (Nine cohort and 18 cross-sectional studies) that reported odds ratios (ORs) comparing the risk of hypertension in shift workers.

Also, there was a prespecified subgroup analysis by rotating shift and night shift statuses. A random-effect, generic inverse variance method was used to calculate pooled OR and 95 percent CI.

The observational studies involved a total of 394,793 individuals. The pooled OR of hypertension in shift workers was 1.31 (95 percent CI, 1.07 to 1.60) in cohort and 1.10 (1.00 to 1.20) in cross-sectional studies.

Upon restriction of the meta-analysis only to cohort studies in the rotating shift, the pooled OR of hypertension in rotating shift workers was 1.34 (1.08 to 1.67). The data was limited with respect to night shift and hypertension in cohort studies. Finally, night shift workers in cross-sectional studies had a pooled hypertension OR of 1.07 (0.85 to 1.35).

A prior meta-analysis of nine observational studies including 112,267 individuals revealed that daytime napping was significantly associated with hypertension. When meta-analysis was limited only to studies assessing the risk of hypertension in daytime nappers, the pooled risk ratio of hypertension was 1.19 (1.06 to 1.35). [J Evid Based Med 2016;9:205-212]

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Most Read Articles
10 Jan 2018
Shared decision support with the use of standardized decision aids improves decision quality and reduces implantation of left ventricular assist device as destination therapy (DT-LVAD) in patients with advanced heart failure.
21 Dec 2017
Physicians’ practice patterns in managing hypertension, and their awareness of blood pressure variability, were reported in a recent study in Singapore. We discussed some of the clinical practice gaps identified by this study with author, A/Prof. Teo Boon Wee.
10 Jan 2018

A new batch of apolipoprotein B (apoB)-lowering drugs that capitalize on statins’ ability to lower lipids will further benefit patients at high cardiovascular (CV) risk who need to be treated more aggressively.

Pearl Toh, 15 Dec 2017
Blood pressure (BP) readings appeared to be similar regardless of whether BP measurements were attended or unattended by staff, nor were CV outcomes different between the two techniques, according to a post hoc survey on participants following the SPRINT* trial.