Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Pearl Toh, 26 Nov 2020
Inhaled corticosteroid (ICS) should be the mainstay of long-term asthma management — such is the key message of the latest Singapore ACE* Clinical Guidance (ACG) for asthma, released in October 2020.
2 days ago
Among patients with moderate-to-severe psoriasis, the use of biologics appears to lower the risk of being hospitalized for the novel coronavirus disease (COVID-19), a new study has found.

Robot-assisted retroperitoneal lymph node dissection feasible for metastatic testicular cancer

11 Dec 2020

A robotic-assisted retroperitoneal lymph node dissection (RARLND) is technically feasible and recommended in highly selected patients with low volume metastatic testicular cancer, suggests a study. In addition, RARLND has comparable complications and early oncologic safety to open surgery.

“RARLND in patients with testicular cancer is controversial. Lately, unusual recurrence patterns with adverse outcomes after RARLND have been published,” the investigators said.

Twenty-seven consecutive patients with small volume metastatic testicular cancer (October 2010 to November 2019) who underwent RARLND (unilateral modified template) were retrospectively evaluated in this study. Intra- and postoperative complications and early oncologic outcomes were reported.

The investigators performed surgery in the primary metastatic setting in 22 patients (81 percent), postchemotherapy in four (15 percent), and for late relapse in one (4 percent). Initial clinical stage was IIA for 14 patients (52 percent), IIB for 12 (43 percent), and III for one (4 percent).

Median operative time was 175 minutes, blood loss 50 ml, and length of hospital stay 4 days. Of the 27 patients, 21 (78 percent) had a viable tumour and six (22 percent) showed fibrosis, necrosis, or no tumour. Three patients (11 percent) had intraoperative (Satava II) and one (4 percent) had postoperative (Clavien-Dindo IIb) complications.

Over a median follow-up of 16.5 months, three patients (11 percent) had relapse outside of the surgical field after 12, 22, and 36 months.

“Prospective data collection in larger series is necessary to clarify the role and specific indications of this approach,” the investigators said.

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Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Pearl Toh, 26 Nov 2020
Inhaled corticosteroid (ICS) should be the mainstay of long-term asthma management — such is the key message of the latest Singapore ACE* Clinical Guidance (ACG) for asthma, released in October 2020.
2 days ago
Among patients with moderate-to-severe psoriasis, the use of biologics appears to lower the risk of being hospitalized for the novel coronavirus disease (COVID-19), a new study has found.