Most Read Articles
Dr. Joseph Delano Fule Robles, 14 Nov 2017

A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated. 

14 Nov 2017
The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.
6 days ago
Both hatha yoga and a low-FODMAP (Fermentable, Oligo-, Di-, Monosaccharides and Polyol) diet can alleviate gastrointestinal symptoms, as well as improve a range of other psychological and physiological health parameters, in patients with irritable bowel syndrome (IBS), a study has shown.
6 days ago
Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.

Risk of VTE higher in patients with primary Sjögren syndrome

31 Aug 2017

Population-based evidence shows a substantially increased risk of venous thromboembolism (VTE) among patients with primary Sjögren syndrome (pSS), especially within the first year after SS diagnosis.

Researchers created a study cohort of all patients with incident SS using a population database that includes all residents of British Columbia, Canada, and up to 10 controls from the general population matched for age, sex and entry time to estimate the future risk and time trends of VTE in individuals with newly diagnosed PSS.

Incidence rates (IRs) of pulmonary embolism (PE), deep vein thrombosis (DVT) and VTE were compared between the two groups according to SS disease duration. Hazard ratio (HR) was also calculated, adjusting for confounders.

Of the 1,175 incident pSS cases (mean age 56.7 years; 87.6 percent women), the respective IRs of PE, DVT and VTE were 3.9, 2.8 and 5.2 per 1,000 person-years. The corresponding rates among controls were 0.9, 0.8 and 1.4 per 1,000 person-years.

In comparison with non-SS individuals, the multivariable HR among SS cases was 4.07 (95 percent CI, 2.04 to 8.09) for PE, 2.80 (1.27 to 6.17) for DVT and 2.92 (1.66 to 5.16) for VTE. The HR matched for age, sex and entry for VTE (8.29; 2.57 to 26.77), PE (4.72; 1.13 to 19.73) and DVT (7.34; 2.80 to 19.25) were highest during the first year after SS diagnosis.

According to researchers, further studies into the involvement of monitoring and prevention of VTE in SS may be warranted.

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Most Read Articles
Dr. Joseph Delano Fule Robles, 14 Nov 2017

A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated. 

14 Nov 2017
The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.
6 days ago
Both hatha yoga and a low-FODMAP (Fermentable, Oligo-, Di-, Monosaccharides and Polyol) diet can alleviate gastrointestinal symptoms, as well as improve a range of other psychological and physiological health parameters, in patients with irritable bowel syndrome (IBS), a study has shown.
6 days ago
Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.