Most Read Articles
Roshini Claire Anthony, 4 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 19 May 2018
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
2 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
3 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.

Ring-shaped allografts effective, safe for adolescent kyphosis

19 Jul 2017

Ring-shaped allografts have good mechanical strength and vertical fusion, and are effective for treating adolescent kyphosis, a new retrospective study reveals.

Mean baseline kyphosis deformity in 25 patients (mean age 13.5 years) was 65o (40o to 97o) of Cobb’s angle. Over a follow up of 3 (2 to 5) years, mean correction following surgery was 51o yielding a postoperative mean deformity of 14o (10o to 21o).

Only one case of growth-induced junctional kyphosis (<10o) was reported and did not affect the appearance of the spine. There were no other cases of graft rejection and adverse outcomes.

All numbness disappeared by the final follow-up and all patients achieved complete bone fusion 3 months after the surgery.

The most common region involved was the lumbar region (n=9) followed by the thoracolumbar (n=8), thoracic (n=5) and cervical (n=3) regions.

While numbness was present in all patients, numbness and radicular pain around the thorax, and weakness of the lower limbs were observed in three participants. Radicular pain was also reported in two of the participants with cervical involvement. There were no cases of cauda equine syndrome or dystaxia.

The study included adolescent patients with spinal tuberculosis and who were undergoing surgery for kyphosis and nerve dysfunction. Antituberculosis drugs were administered to each patient 6 weeks before the surgery.

Cobb’s angle measurement and computed tomography for spinal infusion were performed during monthly follow-ups. Other relevant baseline demographic and medical information were retrieved from medical records.

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Most Read Articles
Roshini Claire Anthony, 4 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 19 May 2018
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
2 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
3 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.