Most Read Articles
2 days ago
Dairy consumption during adolescence or early adulthood does not appear to be associated with the overall risk of breast cancer, although results vary by hormone receptor status of tumours, a study has shown. Specifically, dairy intake is linked to higher ER–/PR– and lower ER+/PR+ cancer risk.
Roshini Claire Anthony, 5 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

3 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
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Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.

Rheumatoid arthritis ups risk of CVD, CHF

11 Jul 2017
Mesoblast cell treatment shows promise for rheumatoid arthritis

The risks of cardiovascular disease (CVD) and congestive heart failure (CHF) are twice as higher in rheumatoid arthritis (RA) patients than in osteoarthritis (OA) patients, a new cross-sectional study in a Chinese population shows.

Comparing the medical records of 1,022 OA (mean age 58.5±0.4 years; 68.7 percent female) and RA (mean age 57.8 years; 68. Percent female) patients, matched by sex and age, a significantly higher prevalence of CVD (adjusted OR [OR], 2.19; 95 percent CI, 1.49 to 2.95; p<0.05) in the RA cohort was found.

CHF (adjusted OR, 6.95; 1.50 to 32.21; p<0.05) and atherosclerosis (adjusted OR, 4.95; 3.36 to 7.28; p<0.05) were also significantly more common in RA vs OA patients.

There was no significant difference in the prevalence of ischaemic heart disease (adjusted OR, 1.83; 0.94 to 3.56) and stroke (adjusted OR, 1.13; 0.57 to 2.25).

Before matching, the prevalence of CVD (adjusted OR, 1.86; 1.42 to 2.43; p<0.05) was also significantly greater in RA (n=1,824; mean age 52.4±0.5 years; 96.9 percent female) than in OA (n=1,995; mean age 63.0±0.3 years; 74.6 percent female) patients.

Similar trends were reported for CHF (adjusted OR, 2.09; 1.03 to 4.22; p<0.05) and atherosclerosis (adjusted OR, 2.49; 1.97 to 3.13; p<0.05).

The medical record database of Sichuan’s provincial people’s hospital was scoured for inpatients with principal diagnoses of RA or OA. Those principally diagnosed with both RA and OA were excluded.

Stroke and CVD were the primary outcomes while specific CVDs, such as IHD, atherosclerosis and CHF, were the secondary outcomes.

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Most Read Articles
2 days ago
Dairy consumption during adolescence or early adulthood does not appear to be associated with the overall risk of breast cancer, although results vary by hormone receptor status of tumours, a study has shown. Specifically, dairy intake is linked to higher ER–/PR– and lower ER+/PR+ cancer risk.
Roshini Claire Anthony, 5 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

3 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
4 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.