Most Read Articles
Stephen Padilla, 4 days ago
Diabetic patients in a decompensated state and who develop type 2 myocardial infarction (MI) have an increased risk for mortality and major adverse cardiac events (MACE), according to a new study. In addition, these patients are potentially at risk for undiagnosed coronary artery disease.
6 days ago
Chocolate consumption is not associated with risk of coronary heart disease (CHD), stroke or both combined in postmenopausal women free of pre-existing major chronic disease, a study suggests.
Pearl Toh, 13 Jul 2018
More intensive lowering of LDL-C levels was associated with a progressively greater survival benefit than less intensive approach, when the baseline LDL-C levels were ≥100 mg/dL, reveals a meta-analysis of 34 randomized trials.
6 days ago
Switching from thiazide diuretic to ipragliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, leads to improvements in metabolic parameters and body mass composition without affecting blood pressure in type 2 diabetes (T2D) patients, a recent study has found.

Resting heart rate tied to hypertension, heart failure

16 Apr 2018

Results of a recent meta-analysis have shown a linear positive relationship between resting heart rate and the incidence of hypertension and heart failure.

There were 13 cohort studies for hypertension and 17 for heart failure included in this study. The respective risk for each disease increased by 11 percent (relative risk [RR], 1.11; 95 percent CI, 1.07–1.15) and 19 percent (RR, 1.19; 1.13–1.25) for each 10 beats-per-minute increment in resting heart rate.

Most subgroup analyses, except for gender subgroups, showed a consistent association between resting heart rate and hypertension or heart failure, with no significant relationship seen in the women subgroup. Furthermore, there was no evidence supporting a nonlinear association of elevated resting heart rate with hypertension and heart failure risk.

The investigators performed a dose-response meta-analysis of studies focusing on risks associated with resting heart rate and hypertension or heart failure. PubMed, Embase, CNKI and WanFang databases were searched for articles published before 15 June 2017.

RRs and 95 percent CIs were pooled using a random-effects model. Restricted cubic spline analysis was conducted to model the resting heart rate-hypertension and heart failure risk association.

In a previous meta-analysis, results showed that higher resting heart rate was independently associated with increased risks of all-cause and cardiovascular mortality, indicating that resting heart rate is a predictor of all-cause and cardiovascular death in the general population. [CMAJ 2016;188:E53-63]

Another study found that higher resting heart rate correlated with both cardiovascular and noncardiovascular mortality. The findings suggest that resting heart rate may be a marker of overall well-being rather than a marker of cardiovascular health. [Am J Cardiol 2017;119:1003-1007]

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Most Read Articles
Stephen Padilla, 4 days ago
Diabetic patients in a decompensated state and who develop type 2 myocardial infarction (MI) have an increased risk for mortality and major adverse cardiac events (MACE), according to a new study. In addition, these patients are potentially at risk for undiagnosed coronary artery disease.
6 days ago
Chocolate consumption is not associated with risk of coronary heart disease (CHD), stroke or both combined in postmenopausal women free of pre-existing major chronic disease, a study suggests.
Pearl Toh, 13 Jul 2018
More intensive lowering of LDL-C levels was associated with a progressively greater survival benefit than less intensive approach, when the baseline LDL-C levels were ≥100 mg/dL, reveals a meta-analysis of 34 randomized trials.
6 days ago
Switching from thiazide diuretic to ipragliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, leads to improvements in metabolic parameters and body mass composition without affecting blood pressure in type 2 diabetes (T2D) patients, a recent study has found.