Most Read Articles
Roshini Claire Anthony, 29 May 2020

For coffee drinkers, drinking filtered coffee may be tied to a lower mortality risk, including cardiovascular disease (CVD)-related mortality, a study from Norway suggested.

4 days ago
Use of corticosteroid is not associated with improved outcomes in idiopathic pulmonary fibrosis (IPF) patients admitted to the hospital with acute exacerbation (AE), reveals a recent study. In addition, corticosteroids may even contribute to reduced overall survival following exacerbation.
Dr. Wong Soon Tee, 28 May 2020
Acne is a common skin problem seen in primary care. Dr Wong Soon Tee of Assurance Skin Clinic at Mt Elizabeth Novena Hospital, Singapore shares his insights with Pearl Toh on how to manage acne in the primary care setting.
27 May 2020
The perception that proton pump inhibitors (PPIs) cause multiple serious adverse effects (AEs) is supported by many internists, who then recommend treatment cessation even in patients at high risk for upper gastrointestinal bleeding (UGIB), reveals a study.

Resection poses greater mortality risks in older PDAC patients

14 May 2020

Older patients with high comorbidity scores face greater mortality risks when undergoing pancreaticoduodenectomy, a recent study has shown.

Researchers conducted a retrospective analysis of 6,149 elderly patients (mean age, 64.9±12.3 years) with pancreatic ductal adenocarcinoma (PDAC). The study outcome of interest was 30-day in-hospital mortality.

Overall, the rate of 30-day in-hospital mortality was 3.24 percent. This was higher in patients older than 76 years (4.11 percent vs 2.77 percent). This corresponded to a significantly greater mortality risk in older patients (odds ratio [OR], 1.46, 95 percent confidence interval [CI], 1.07–2.00; p=0.016).

Morbidity, defined as a history of infectious and parasitic diseases, and diseases of the circulatory and respiratory systems, was also a significant risk factor for mortality (OR, 7.16, 95 percent CI, 3.75–13.68; p<0.01). Length of stay also emerged as an inverse predictor (OR, 0.97, 95 percent CI, 0.95–0.99; p=0.006).

The mean length of hospital stay was 13±11 days. This was significantly longer in patients aged >76 years (14.5±10.9 vs 13.1±10.4 days; p<0.001). Age, sex, ethnicity and a history of prior illnesses were found as independent predictors of a longer hospital stay.

“The current study is the largest dataset evaluating the impact of age on the mortality of patients with PDAC undergoing resection,” the researchers said.

“When considering whether to pursue a curative approach, physicians must consider the overall health and performance status of the patient and, while not necessarily a defining factor, patient physiologic and chronologic age are two factors in this overall evaluation,” they added.

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Most Read Articles
Roshini Claire Anthony, 29 May 2020

For coffee drinkers, drinking filtered coffee may be tied to a lower mortality risk, including cardiovascular disease (CVD)-related mortality, a study from Norway suggested.

4 days ago
Use of corticosteroid is not associated with improved outcomes in idiopathic pulmonary fibrosis (IPF) patients admitted to the hospital with acute exacerbation (AE), reveals a recent study. In addition, corticosteroids may even contribute to reduced overall survival following exacerbation.
Dr. Wong Soon Tee, 28 May 2020
Acne is a common skin problem seen in primary care. Dr Wong Soon Tee of Assurance Skin Clinic at Mt Elizabeth Novena Hospital, Singapore shares his insights with Pearl Toh on how to manage acne in the primary care setting.
27 May 2020
The perception that proton pump inhibitors (PPIs) cause multiple serious adverse effects (AEs) is supported by many internists, who then recommend treatment cessation even in patients at high risk for upper gastrointestinal bleeding (UGIB), reveals a study.