Most Read Articles
09 Nov 2017
Treatment with fesoterodine shows efficacy in patients with nocturnal urgency secondary to overactive bladder syndrome and low nocturnal bladder capacity with a mismatch between nocturnal urine production and bladder capacity, reports a recent study.
Pearl Toh, 3 days ago
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
04 Jan 2018
Statins appear to reduce the severity of acute pancreatitis (AP), as demonstrated by a decrease in overall incidence of multisystem organ failure (MSOF), according to a study.
Elvira Manzano, 22 Nov 2017
A blood pressure (BP) reading of 130/80 mm Hg or higher is the ‘new high’ in the latest AHA/ACC* hypertension guidelines, a threshold that is tighter than the JNC 7** cutpoint of 140/90 mm Hg for stage 1 hypertension in the general population. The change will mean more patients being labelled with hypertension.

Repeated vaccination effective in protecting against severe influenza

09 Jan 2018

Repeated influenza vaccination is effective in preventing severe vs nonsevere influenza infections in elderly adults, a recent multicentre, case-control study has shown.

The study included 130 and 598 patients with severe and nonsevere influenza, who were then matched to 333 and 1,493 controls, respectively.

Vaccination in the current season and at least one of the three previous seasons led to significantly lower odds of severe disease (adjusted odds ratio [OR], 0.45; 95 percent CI, 0.26–0.76; p=0.003), intensive care unit (ICU) admission (adjusted OR, 0.35; 0.17–0.70; p=0.003) and death (adjusted OR, 0.44; 0.23–0.86; p=0.02).

In comparison, those who were only vaccinated in the current season did not reduce risks of severe disease (adjusted OR, 2.22; 0.89–5.51; p=0.09) and ICU admissions (adjusted OR, 1.14; 0.34–3.87; p=0.8), and had significantly higher risk of death (adjusted OR, 3.35; 1.06–10.58; p=0.04).

Moreover, those who were unvaccinated were admitted to the ICU more frequently (16 vs 6 percent; p<0.001) compared with those who were vaccinated. Mortality rates within the first 30 days after admission were also higher in unvaccinated participants (14 vs 9 percent; p=0.04).

In terms of hospital admissions, those who were vaccinated in the current season and in any of the three previous seasons were less likely to be admitted to the hospital for nonsevere influenza (31 percent effectiveness). Effectiveness estimates were higher for preventing ICU admission (74 percent) and death (70 percent).

Furthermore, those who were vaccinated in the current season only were not significantly protected against severe influenza.

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Most Read Articles
09 Nov 2017
Treatment with fesoterodine shows efficacy in patients with nocturnal urgency secondary to overactive bladder syndrome and low nocturnal bladder capacity with a mismatch between nocturnal urine production and bladder capacity, reports a recent study.
Pearl Toh, 3 days ago
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
04 Jan 2018
Statins appear to reduce the severity of acute pancreatitis (AP), as demonstrated by a decrease in overall incidence of multisystem organ failure (MSOF), according to a study.
Elvira Manzano, 22 Nov 2017
A blood pressure (BP) reading of 130/80 mm Hg or higher is the ‘new high’ in the latest AHA/ACC* hypertension guidelines, a threshold that is tighter than the JNC 7** cutpoint of 140/90 mm Hg for stage 1 hypertension in the general population. The change will mean more patients being labelled with hypertension.