Most Read Articles
4 days ago
Poor overall diet quality, particularly low intake of vegetable protein, appears to put elderly adults at greater risk of frailty, a recent study has found.
Pearl Toh, 15 Jul 2019
In addition to the known evils of maternal smoking during pregnancy on the son’s semen quality, prenatal exposure to paternal smoking can also be harmful, according to data from the large Danish National Birth Cohort (DNBC) presented at the ESHRE 2019 Meeting.
3 days ago
Health-related quality of life (HRQoL) among patients with kidney stone is worse in those who are young and female than those who are older and male, according to a recent study. Non-Caucasian patients also have a lower HRQoL.
Tristan Manalac, 4 days ago
In patients with ST-segment elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PPCI), admission Killip classification and creatinine and troponin levels are important cardiac mortality predictors, according to a recent Singapore study.

Repeat imaging of sacroiliac joints not useful in diagnostic workup of axSpA

01 Oct 2018

The usefulness of repeating magnetic resonance imaging (MRI) of the sacroiliac joints (MRI-SI) after 3 months or 1 year in the diagnostic workup of chronic back pain patients suspected of axial spondyloarthritis (axSpA) appears to be limited, according to data from the SPACE cohort. Specifically, only a small percentage of patients exhibit changes in MRI-SI status.

A total of 188 patients with chronic back pain (mean age 31.0 years; 38.3 percent male; symptom duration, 13.2 months) underwent evaluation of all SpA‐features and repeated MRI‐SI at baseline, 3 months and 1 year. Thirty-one patients (16.5 percent) were MRI‐SI‐positive at baseline. MRI‐SI positivity was evaluated according to Assessment of SpondyloArthritis International Society (ASAS).

MRI-SI status changed from positive to negative in 3/27 patients (11.1 percent) after 3 months and in 11/29 patients (37.9 percent) after 1 year. This change was partly induced by antitumour necrosis factor therapy initiation.

On the other hand, status changed from negative to positive in 5/116 patients (4.3 percent) after 3 months and in 10/138 patients (7.2 percent) after 1 year.

On generalized estimating equation analysis, HLA‐B27‐positivity and male gender emerged as independent determinants of a positive MRI-SI at any time point (42 percent in HLA‐B27-positive males; 6 percent in HLA‐B27-negative females).

Meanwhile, MRI-SI status at baseline strongly predicted MRI-SI status at follow-up, such that a negative status at baseline predicted a very low likelihood of a positive MRI during follow‐up (max, 7 percent).

The present data suggest that the usefulness of repeating a negative MRI in terms of diagnostic yield is low, although there are different risks related to sex and HLA-B27 status, researchers said.

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Most Read Articles
4 days ago
Poor overall diet quality, particularly low intake of vegetable protein, appears to put elderly adults at greater risk of frailty, a recent study has found.
Pearl Toh, 15 Jul 2019
In addition to the known evils of maternal smoking during pregnancy on the son’s semen quality, prenatal exposure to paternal smoking can also be harmful, according to data from the large Danish National Birth Cohort (DNBC) presented at the ESHRE 2019 Meeting.
3 days ago
Health-related quality of life (HRQoL) among patients with kidney stone is worse in those who are young and female than those who are older and male, according to a recent study. Non-Caucasian patients also have a lower HRQoL.
Tristan Manalac, 4 days ago
In patients with ST-segment elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PPCI), admission Killip classification and creatinine and troponin levels are important cardiac mortality predictors, according to a recent Singapore study.