Most Read Articles
4 days ago
The consumption of red and processed meats does not seem to affect the likelihood of symptom relapse among Crohn’s disease (CD) patients in relapse, reports a recent study.
Roshini Claire Anthony, 10 Jul 2019

Women who receive a single dose of amoxicillin and clavulanic acid within 6 hours of operative vaginal delivery could significantly reduce their postpartum infection risk, according to the UK-based ANODE* trial.

Pearl Toh, Yesterday
In addition to the known evils of maternal smoking during pregnancy on the son’s semen quality, prenatal exposure to paternal smoking can also be harmful, according to data from a large Danish National Birth Cohort (DNBC) presented at the ESHRE 2019 Meeting.
4 days ago
Treatment with metformin may improve whole-body and peripheral insulin resistance (IR) in youth who are overweight/obese with type 1 diabetes (T1D), according to a study.

Repeat imaging of sacroiliac joints not useful in diagnostic workup of axSpA

01 Oct 2018

The usefulness of repeating magnetic resonance imaging (MRI) of the sacroiliac joints (MRI-SI) after 3 months or 1 year in the diagnostic workup of chronic back pain patients suspected of axial spondyloarthritis (axSpA) appears to be limited, according to data from the SPACE cohort. Specifically, only a small percentage of patients exhibit changes in MRI-SI status.

A total of 188 patients with chronic back pain (mean age 31.0 years; 38.3 percent male; symptom duration, 13.2 months) underwent evaluation of all SpA‐features and repeated MRI‐SI at baseline, 3 months and 1 year. Thirty-one patients (16.5 percent) were MRI‐SI‐positive at baseline. MRI‐SI positivity was evaluated according to Assessment of SpondyloArthritis International Society (ASAS).

MRI-SI status changed from positive to negative in 3/27 patients (11.1 percent) after 3 months and in 11/29 patients (37.9 percent) after 1 year. This change was partly induced by antitumour necrosis factor therapy initiation.

On the other hand, status changed from negative to positive in 5/116 patients (4.3 percent) after 3 months and in 10/138 patients (7.2 percent) after 1 year.

On generalized estimating equation analysis, HLA‐B27‐positivity and male gender emerged as independent determinants of a positive MRI-SI at any time point (42 percent in HLA‐B27-positive males; 6 percent in HLA‐B27-negative females).

Meanwhile, MRI-SI status at baseline strongly predicted MRI-SI status at follow-up, such that a negative status at baseline predicted a very low likelihood of a positive MRI during follow‐up (max, 7 percent).

The present data suggest that the usefulness of repeating a negative MRI in terms of diagnostic yield is low, although there are different risks related to sex and HLA-B27 status, researchers said.

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Most Read Articles
4 days ago
The consumption of red and processed meats does not seem to affect the likelihood of symptom relapse among Crohn’s disease (CD) patients in relapse, reports a recent study.
Roshini Claire Anthony, 10 Jul 2019

Women who receive a single dose of amoxicillin and clavulanic acid within 6 hours of operative vaginal delivery could significantly reduce their postpartum infection risk, according to the UK-based ANODE* trial.

Pearl Toh, Yesterday
In addition to the known evils of maternal smoking during pregnancy on the son’s semen quality, prenatal exposure to paternal smoking can also be harmful, according to data from a large Danish National Birth Cohort (DNBC) presented at the ESHRE 2019 Meeting.
4 days ago
Treatment with metformin may improve whole-body and peripheral insulin resistance (IR) in youth who are overweight/obese with type 1 diabetes (T1D), according to a study.