Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
6 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.
11 Jan 2020
Prevention of glucocorticoid-induced osteoporosis (GIOP) and postmenopausal osteoporosis (PMOP) remains inadequate in patients with rheumatoid arthritis (RA), as shown in a study that evaluated the implementation of the 2003 and 2014 French guidelines on the prevention and treatment of GIOP and the 2012 update of the French guidelines for the treatment of PMOP.

Renal disease among diabetics heterogenous

09 Oct 2019

In diabetic adults, the presentation of renal disease is heterogenous and involves different mechanisms of action, a new Japan study has found.

Drawing data from 355 patients with type 1 diabetes and 5,194 with type 2 diabetes, researchers determined the prevalence of renal dysfunction and albuminuria, as well as related factors. Those undergoing dialysis, with malignant disease or who had proliferative diabetic retinopathy were ineligible.

Of the type 1 diabetes participants, majority (n=290; mean age, 56±9 years; 43.4 percent male) had normal urinary albumin levels, while 65 (mean age, 58±8 years; 46.2 percent male) were either micro- or macroalbuminuric. In those with type 2 disease, 3,631 (mean age, 61±8 years; 59.0 percent male) were normoalbuminuric while 1,563 (mean age, 62±8 years 59.4 percent male) had abnormal levels of albumin in the urine.

Renal dysfunction, defined as estimated glomerular filtration rate (eGFR) <60 mL/min/1.73m2, without albuminuria was present in 7.3 percent and 9.0 percent of type 1 and 2 diabetes patients, respectively.

Logistic regression analysis further found that in type 1 diabetes, the duration of the endocrinal disease (p=0.009) and the presence of or a history of hypertension (p=0.005) were significant indicators of albuminuria, while age (p<0.001) and disease duration (p=0.023) were significantly correlated with lowered eGFR.

In type 2 diabetes, on the other hand, significant predictors of albuminuria were age (p=0.017), duration of diabetes (p<0.001), the presence of or a history of hypertension (p<0.001), body mass index (p<0.001), glycated haemoglobin (p<0.001), and eGFR (p<0.001). The male sex (p<0.001), age (p<0.001), albuminuria (p<0.001) and regular alcohol intake (p<0.001) were all associated with renal dysfunction.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
6 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.
11 Jan 2020
Prevention of glucocorticoid-induced osteoporosis (GIOP) and postmenopausal osteoporosis (PMOP) remains inadequate in patients with rheumatoid arthritis (RA), as shown in a study that evaluated the implementation of the 2003 and 2014 French guidelines on the prevention and treatment of GIOP and the 2012 update of the French guidelines for the treatment of PMOP.