Most Read Articles
Stephen Padilla, 05 Jan 2018
The addition of an antihypertensive drug from a new class to a patient’s regimen results in huge decreases in systolic blood pressure (SBP) and major cardiovascular (CV) events among those at high risk for CV events but without diabetes, suggests a recent study. Its effects on SBP remain large and similar in magnitude across all levels of baseline drug use and all subgroups of patients.
Pearl Toh, 3 days ago
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
04 Jan 2018
Thromboembolism is a major cause of death in patients with cancer, which is why clinicians should check for the symptoms of thromboembolic events right from the initial stages of bevacizumab treatment, suggests a recent study.
04 Jan 2018
Statins appear to reduce the severity of acute pancreatitis (AP), as demonstrated by a decrease in overall incidence of multisystem organ failure (MSOF), according to a study.

Regular aerobic exercise reduces efficacy of iron supplementation

3 days ago

Aerobic training on a regular basis lessens the apparent effectiveness of iron supplementation in improving serum ferritin (sFer), leaving doubts on whether conventional measures of iron status accurately reflect iron metabolism in physically active, nonanaemic women, suggests a study.

Individuals in both the iron-supplemented trained and untrained groups, compared with either of the placebo groups, had significantly improved sFer, soluble transferrin receptor (sTfR) and body iron values following treatment. Trained participants also had significantly greater aerobic fitness measures than untrained participants.

The sFer response to supplementation changed with training (p=0.07), with the iron-supplemented trained group showing significantly lower sFer than the iron-supplemented untrained group at week 8 (mean, 31.8 and 47.6 μg/L, respectively; p=0.042). However, no significant difference was observed between the placebo trained and untrained groups (mean, 21.3 and 20.3 μg/L, respectively; p=1.00).

The authors enrolled 72 iron-depleted, nonanaemic Chinese women (sFer <25 μg/L and haemoglobin >110 g/L) in an 8-week, partially blinded, randomized controlled trial with a 2x2 factorial design including iron supplements (42 mg elemental Fe/day) or placebo and aerobic training (five 25-min sessions/week at 75‒85 percent of maximum heart rate) or no training.

They examined the association between supplement type, training and changes in iron over time (measured by sFer, haemoglobin, sTfR and estimated total body iron) using linear mixed models.

“Despite its known detrimental effects, iron deficiency remains the most common micronutrient deficiency in the world. Many interventions that aim to improve iron status involve physically active populations. Intense aerobic exercise training negatively affects iron status,” the authors said.

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Most Read Articles
Stephen Padilla, 05 Jan 2018
The addition of an antihypertensive drug from a new class to a patient’s regimen results in huge decreases in systolic blood pressure (SBP) and major cardiovascular (CV) events among those at high risk for CV events but without diabetes, suggests a recent study. Its effects on SBP remain large and similar in magnitude across all levels of baseline drug use and all subgroups of patients.
Pearl Toh, 3 days ago
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
04 Jan 2018
Thromboembolism is a major cause of death in patients with cancer, which is why clinicians should check for the symptoms of thromboembolic events right from the initial stages of bevacizumab treatment, suggests a recent study.
04 Jan 2018
Statins appear to reduce the severity of acute pancreatitis (AP), as demonstrated by a decrease in overall incidence of multisystem organ failure (MSOF), according to a study.