Most Read Articles
5 days ago
An association exists between Ramadan fasting and reduced activity and sleeping time, suggests a study, adding that no significant change is seen in resting metabolic rate (RMR) and total energy expenditure (TEE).
13 May 2018
Maternal hypothyroidism contributes to an increased risk of developing autism spectrum disorder in children in a manner dependent on race–ethnicity, according to a retrospective US cohort study.
Jairia Dela Cruz, 3 days ago
Male smokers under the age of 50 years are at risk of developing ischaemic stroke, and this risk increases with the number of cigarettes smoked daily, according to data from the Stroke Prevention in Young Men Study.
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While caudal block does not pose serious safety threats, it also does not seem to significantly improve pain control or reduce analgesic use in patients following robot-assisted laparoscopic radical prostatectomy (RARP), a recent Singapore study has shown.

Regression of cervical intraepithelial neoplasia higher in younger women

02 May 2018

Regression rates of cervical intraepithelial neoplasia (CIN) appear to be significantly elevated in younger females, a recent study has shown. Moreover, the effect of age is independent of risk of human papillomavirus (HPV) and CIN grade.

In the study cohort of 783 females, rates of regression were highest in those aged <25 years (n=141; 44.68 percent) and decreased to 33.71 percent in those aged ≥25 to <30 years (n=178). Regression rates continued to drop as age increased: ≥30 to <35 years (n=152; 30.92 percent), ≥35 to <40 years (n=139; 27.34 percent) and ≥40 years (n=173; 24.85 percent; p<0.001 for trend).

Similarly, complete remission was highest in the youngest age group (39.72 percent) and decreased significantly with increasing age (≥25 to <30 years: 29.21 percent; ≥30 to <35 years: 25.66 percent; ≥35 to <40 years: 22.30 percent; ≥40 years: 23.12 percent; p<0.001 for trend).

Disease progression showed the inverse trend: rates were highest in the ≥40 years age group (24.86 percent) and decreased with age; only 10.64 percent of the participants <25 years of age showed progression (p=0.003 for trend).

Multivariable logistic regression confirmed the above trends. Per 5-year increase in age, there was a significant 11-percent decrease in the likelihood of regression (odds ratio, 0.89; 95 percent CI, 0.79–0.99; p=0.049). This association was independent of CIN grade and HPV high-risk infection status.

“Observational management should be considered for selected young women who plan future childbearing,” said researchers.

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Most Read Articles
5 days ago
An association exists between Ramadan fasting and reduced activity and sleeping time, suggests a study, adding that no significant change is seen in resting metabolic rate (RMR) and total energy expenditure (TEE).
13 May 2018
Maternal hypothyroidism contributes to an increased risk of developing autism spectrum disorder in children in a manner dependent on race–ethnicity, according to a retrospective US cohort study.
Jairia Dela Cruz, 3 days ago
Male smokers under the age of 50 years are at risk of developing ischaemic stroke, and this risk increases with the number of cigarettes smoked daily, according to data from the Stroke Prevention in Young Men Study.
Tristan Manalac, 14 May 2018
While caudal block does not pose serious safety threats, it also does not seem to significantly improve pain control or reduce analgesic use in patients following robot-assisted laparoscopic radical prostatectomy (RARP), a recent Singapore study has shown.