Most Read Articles
14 Aug 2018
Patients with coronary artery disease (CAD) treated in a poor Southeast Asian setting appear to have far too high short-term and medium-term mortality rates, according to a study.
2 days ago
Despite the absence of a substance use problem, regular cannabis use is associated with psychosocial impairment among adolescents and young adults, a study suggests. On the other hand, regular users with cannabis use disorder appear to exhibit high psychiatric comorbidity and more severe psychosocial impairment.
4 days ago
Heeding the advice to eat more vegetables has led to an increase in consumption above the Australian Dietary recommendation of ~375 g/day among overweight participants, a recent study has shown. Tomatoes are a common choice regardless of the time of year, but selections change over time.
21 Jul 2018
Although many patients with atopic dermatitis (AD) use antihistamines, no high-level evidence exists to prove that nonsedating antihistamines reduce itch in patients with AD or provide benefit in controlling AD symptoms, except perhaps sleep and AD comorbidities such as allergic rhinitis, according to a study.

Regression of cervical intraepithelial neoplasia higher in younger women

02 May 2018

Regression rates of cervical intraepithelial neoplasia (CIN) appear to be significantly elevated in younger females, a recent study has shown. Moreover, the effect of age is independent of risk of human papillomavirus (HPV) and CIN grade.

In the study cohort of 783 females, rates of regression were highest in those aged <25 years (n=141; 44.68 percent) and decreased to 33.71 percent in those aged ≥25 to <30 years (n=178). Regression rates continued to drop as age increased: ≥30 to <35 years (n=152; 30.92 percent), ≥35 to <40 years (n=139; 27.34 percent) and ≥40 years (n=173; 24.85 percent; p<0.001 for trend).

Similarly, complete remission was highest in the youngest age group (39.72 percent) and decreased significantly with increasing age (≥25 to <30 years: 29.21 percent; ≥30 to <35 years: 25.66 percent; ≥35 to <40 years: 22.30 percent; ≥40 years: 23.12 percent; p<0.001 for trend).

Disease progression showed the inverse trend: rates were highest in the ≥40 years age group (24.86 percent) and decreased with age; only 10.64 percent of the participants <25 years of age showed progression (p=0.003 for trend).

Multivariable logistic regression confirmed the above trends. Per 5-year increase in age, there was a significant 11-percent decrease in the likelihood of regression (odds ratio, 0.89; 95 percent CI, 0.79–0.99; p=0.049). This association was independent of CIN grade and HPV high-risk infection status.

“Observational management should be considered for selected young women who plan future childbearing,” said researchers.

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Most Read Articles
14 Aug 2018
Patients with coronary artery disease (CAD) treated in a poor Southeast Asian setting appear to have far too high short-term and medium-term mortality rates, according to a study.
2 days ago
Despite the absence of a substance use problem, regular cannabis use is associated with psychosocial impairment among adolescents and young adults, a study suggests. On the other hand, regular users with cannabis use disorder appear to exhibit high psychiatric comorbidity and more severe psychosocial impairment.
4 days ago
Heeding the advice to eat more vegetables has led to an increase in consumption above the Australian Dietary recommendation of ~375 g/day among overweight participants, a recent study has shown. Tomatoes are a common choice regardless of the time of year, but selections change over time.
21 Jul 2018
Although many patients with atopic dermatitis (AD) use antihistamines, no high-level evidence exists to prove that nonsedating antihistamines reduce itch in patients with AD or provide benefit in controlling AD symptoms, except perhaps sleep and AD comorbidities such as allergic rhinitis, according to a study.