Most Read Articles
Roshini Claire Anthony, 3 days ago

Individuals with moderate-to-severe plaque psoriasis may reap better long-term improvements in the severity of their condition when treated with guselkumab over secukinumab, according to findings of the phase III ECLIPSE* trial presented at the recent Inflammatory Skin Disease Summit (ISDS 2018) held in Vienna, Austria.

Jairia Dela Cruz, 11 Jan 2019
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
04 Jan 2019
Obstructive sleep apnoea may increase the risk of male-pattern baldness in men with a family history of hair loss, and this association appears to be mediated by low serum transferrin saturation levels related to hypoxia, a study suggests.
2 days ago
Discontinuing the use of tyrosine kinase inhibitors (TKIs) in the treatment of patients with chronic myeloid leukaemia appears to be feasible in real-life clinical practice in the context of close molecular monitoring, a study reports.

Red, processed meat intake tied to shorter survival in colorectal cancer

15 Dec 2018

Eating high amounts of red and processed meat prior to a diagnosis of colorectal cancer (CRC) appears to be associated with shorter survival time, although a possible weak association cannot be excluded, a study has shown.

Researchers included 7,627 patients with stage I-IV CRC from 10 studies in the International Survival Analysis in Colorectal Cancer Consortium. They performed Cox proportional hazards regression analysis to evaluate the associations of intake of red and processed meat before diagnosis with overall and CRC-specific survival.

A total of 2,338 patients died over a median follow-up time of 5.1 years, among whom 1,576 had CRC-specific deaths.

In multivariable-adjusted analyses, higher intake level of red or processed meat showed no association with overall survival of patients with stage I–III CRC (Q4 vs Q1 red meat intake: hazard ratio [HR], 1.08; 95 percent CI, 0.93–1.26; Q4 vs Q1 processed meat intake: HR, 1.10; 0.93–1.32) or with CRC-specific survival (Q4 vs Q1 red meat intake: HR, 1.09; 0.89–1.33; Q4 vs Q1 processed meat intake: HR, 1.11; 0.87–1.42). Results were similar for patients with stage IV CRC.

On the other hand, the risk of death from any cause in patients with stage I–III CRC proved to be higher among those who reported an intake of processed meat above the study-specific medians vs those who reported eating at or less than the median (HR, 1.12; 1.01–1.25).

Researchers underscored a need for more studies evaluating dietary data from several time points before and after cancer diagnosis to confirm the present findings.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 3 days ago

Individuals with moderate-to-severe plaque psoriasis may reap better long-term improvements in the severity of their condition when treated with guselkumab over secukinumab, according to findings of the phase III ECLIPSE* trial presented at the recent Inflammatory Skin Disease Summit (ISDS 2018) held in Vienna, Austria.

Jairia Dela Cruz, 11 Jan 2019
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
04 Jan 2019
Obstructive sleep apnoea may increase the risk of male-pattern baldness in men with a family history of hair loss, and this association appears to be mediated by low serum transferrin saturation levels related to hypoxia, a study suggests.
2 days ago
Discontinuing the use of tyrosine kinase inhibitors (TKIs) in the treatment of patients with chronic myeloid leukaemia appears to be feasible in real-life clinical practice in the context of close molecular monitoring, a study reports.