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Roshini Claire Anthony, 3 days ago

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Radical prostatectomy delivers long term effects on intercourse satisfaction

10 Aug 2018

Radical prostatectomy (RP) has enduring effects on erectile dysfunction, but restoration of function may not lead to restoration of intercourse satisfaction, a recent study has found.

Using the International Index of Erectile Function (IIEF), researchers assessed erectile function and intercourse satisfaction in 166 men (mean age 58±7 years) before RP and 24 months after RP. Repeated measures t-tests were used to compare changes in scores. Multivariable analyses were performed to evaluate the correlation between function and satisfaction.

At baseline, mean scores for the Erectile Function (EFD) and Intercourse Satisfaction (ISD) domains of the IIEF were 29±2 and 12, respectively. Both scores significantly dropped to 20±10 (p≤0.01) and 8.3 (p<0.001) by 24 months.

Less than half of the participants (46 percent; n=77) were able to achieve penetration hardness erections (PHE) after 24 months, regardless of the use of phosphodiesterase type 5 inhibitors (PDE5is). An even small percentage were able to achieve PHE without the use of PDE5is (22 percent; n=37).

However, even in men who were able to achieve PHE, ISD scores remained significantly lower at the 24-month follow-up relative to baseline values (11.3 vs 12.3; p<0.001). This was true for men who were (11.7 vs 12.5) or were not (10.8 vs 12.1; p<0.01 for both) taking PDE5is.

Multivariable analysis showed that of all factors considered, only 24-month EFD scores (β, 0.23; p=0.04) and baseline intercourse satisfaction (β, 0.46; p<0.01) were significantly predictive of intercourse satisfaction at 24 months.

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Most Read Articles
Roshini Claire Anthony, 3 days ago

A subgroup of patients with HBeAg-negative chronic hepatitis B virus (HBV) infection who ceased their long-term nucleotide analogue treatment maintained virological suppression, pointing to a group of patients who may be suitable for treatment cessation, according to a recent study.

Rachel Soon, 5 days ago

Gels utilizing Stichopus horrens (golden sea cucumber/gamat) extract show a similar efficacy to standard-of-care hydrogels for promoting wound healing, according to a prospective study.

4 days ago
Higher cancer symptom burden in elderly adults is associated with functional impairment, reports a recent study.
2 days ago
The monoclonal antibody abrilumab is effective for treating moderate-to-severe ulcerative colitis, promoting remission, clinical response and mucosal healing, a recent study has found.