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Quality of life low in adolescents with endometriosis

30 Nov 2018
Debilitating pain is one of the major symptoms of endometriosis that can affect the patient’s quality of life.

Endometriosis significantly impairs quality of life (QoL) in adolescents and young women, especially in those with early menarche and severe pelvic pain, a recent study has found.

Of the 567 participants (aged 10–24 years), 360 had endometriosis while 207 were controls. Current use of over-the-counter pain medications was more common in endometriosis patients than in controls (acetaminophen: 16.4 percent vs 2.9 percent; ibuprofen: 27.2 percent vs 7.7 percent, respectively). Anxiety and depression/mood disorders requiring medication were likewise more common in cases.

Both mean physical (PCS; 43.7±11.2 vs 53.9±7.8; p<0.001) and mental (MCS; 43.5±12.2 vs 46.4±11.1; p=0.01) component summary scores were significantly lower in participants with vs without endometriosis.

Similarly, scores in all eight subscales of the 36-item short-form health survey were significantly lower in endometriosis patients: general health, bodily pain, role limitation-physical, role limitation-emotional, mental health, vitality, and physical and social functioning. Impairment in the bodily pain domain was the most prominent (39.4±11.1 vs 51.9±8.7; p<0.001).

PCS scores were significantly lower among endometriosis patients with severe vs moderate pelvic pain (42.8±11.1 vs 45.9±11.2; p=0.02), while those with severe vs moderate pain had worse MCS scores (42.6±12.1 vs 45.9±12.2; p=0.03).

Moreover, early menarche was also associated with lower PCS scores (<11 vs 12 years: 41.6±11.2 vs 45.7±11.2; p=0.02). This association was driven mostly by physical impairments; no links between age at menarche at mental health-related QoL scores were observed.

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Most Read Articles
04 Feb 2019
The carbon-chain length of saturated fatty acids appears to be an important factor in determining its role in cardiovascular health, a recent study has found.
6 days ago
Olanzapine confers a modest therapeutic effect on weight compared with placebo in adult outpatients with anorexia nervosa, a study has shown. However, it does not appear to offer significant benefit for psychological symptoms.
Pearl Toh, 3 days ago
A latest study at ISC 2019 shows that even patients with large-core stroke damage can have a good outcome after mechanical clot removal with endovascular thrombectomy (EVT), depending on the size of the infarct and time lapses between stroke onset and treatment.
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Treatment with secukinumab results in a higher rate of remission or low-disease activity at week 16 in patients with psoriatic arthritis as compared with placebo, according to a posthoc analysis of the FUTURE 2 study. This effect is sustained at 2 years and is evident in both tumour necrosis factor inhibitor-experienced and -naïve patients.