Quality of life low in adolescents with endometriosis
Endometriosis significantly impairs quality of life (QoL) in adolescents and young women, especially in those with early menarche and severe pelvic pain, a recent study has found.
Of the 567 participants (aged 10–24 years), 360 had endometriosis while 207 were controls. Current use of over-the-counter pain medications was more common in endometriosis patients than in controls (acetaminophen: 16.4 percent vs 2.9 percent; ibuprofen: 27.2 percent vs 7.7 percent, respectively). Anxiety and depression/mood disorders requiring medication were likewise more common in cases.
Both mean physical (PCS; 43.7±11.2 vs 53.9±7.8; p<0.001) and mental (MCS; 43.5±12.2 vs 46.4±11.1; p=0.01) component summary scores were significantly lower in participants with vs without endometriosis.
Similarly, scores in all eight subscales of the 36-item short-form health survey were significantly lower in endometriosis patients: general health, bodily pain, role limitation-physical, role limitation-emotional, mental health, vitality, and physical and social functioning. Impairment in the bodily pain domain was the most prominent (39.4±11.1 vs 51.9±8.7; p<0.001).
PCS scores were significantly lower among endometriosis patients with severe vs moderate pelvic pain (42.8±11.1 vs 45.9±11.2; p=0.02), while those with severe vs moderate pain had worse MCS scores (42.6±12.1 vs 45.9±12.2; p=0.03).
Moreover, early menarche was also associated with lower PCS scores (<11 vs 12 years: 41.6±11.2 vs 45.7±11.2; p=0.02). This association was driven mostly by physical impairments; no links between age at menarche at mental health-related QoL scores were observed.