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Quality of life low in adolescents with endometriosis

30 Nov 2018
Debilitating pain is one of the major symptoms of endometriosis that can affect the patient’s quality of life.

Endometriosis significantly impairs quality of life (QoL) in adolescents and young women, especially in those with early menarche and severe pelvic pain, a recent study has found.

Of the 567 participants (aged 10–24 years), 360 had endometriosis while 207 were controls. Current use of over-the-counter pain medications was more common in endometriosis patients than in controls (acetaminophen: 16.4 percent vs 2.9 percent; ibuprofen: 27.2 percent vs 7.7 percent, respectively). Anxiety and depression/mood disorders requiring medication were likewise more common in cases.

Both mean physical (PCS; 43.7±11.2 vs 53.9±7.8; p<0.001) and mental (MCS; 43.5±12.2 vs 46.4±11.1; p=0.01) component summary scores were significantly lower in participants with vs without endometriosis.

Similarly, scores in all eight subscales of the 36-item short-form health survey were significantly lower in endometriosis patients: general health, bodily pain, role limitation-physical, role limitation-emotional, mental health, vitality, and physical and social functioning. Impairment in the bodily pain domain was the most prominent (39.4±11.1 vs 51.9±8.7; p<0.001).

PCS scores were significantly lower among endometriosis patients with severe vs moderate pelvic pain (42.8±11.1 vs 45.9±11.2; p=0.02), while those with severe vs moderate pain had worse MCS scores (42.6±12.1 vs 45.9±12.2; p=0.03).

Moreover, early menarche was also associated with lower PCS scores (<11 vs 12 years: 41.6±11.2 vs 45.7±11.2; p=0.02). This association was driven mostly by physical impairments; no links between age at menarche at mental health-related QoL scores were observed.

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Most Read Articles
5 days ago
A strong belief in the necessity of medication is associated with better adherence to oral disease-modifying antirheumatic drugs (DMARDs) or prednisone, while higher self-efficacy correlates with poor adherence, in a diverse cohort of patients with rheumatoid arthritis (RA), suggests a study.
4 days ago
Low-dose administrations of haloperidol after thoracic surgery does not appear to prevent postoperative delirium, according to a new study.
2 days ago
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Pearl Toh, 4 days ago
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