Most Read Articles
Roshini Claire Anthony, 2 days ago

Patients undergoing chemotherapy for breast or haematological cancers could potentially reduce their risk of chemotherapy-related cardiotoxicity with the use of angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor antagonists (ARBs), or beta-blockers as primary prevention, according to a systematic review and meta-analysis presented at the recent EuroEcho 2019 conference.

Tristan Manalac, 3 days ago
Users of electronic nicotine delivery systems are likely to have received a diagnosis of clinical depression in the past, according to a recent study.
Pearl Toh, 06 Dec 2019
Getting just under one extra hour of sleep per night can go a long way for the health of college students, who are often sleep-deprived, a study suggests.
6 days ago
While douching is not associated with the risk of ovarian cancer, the combination of talc and commercially available douches contributes to a modest increase in the risk of epithelial ovarian cancer beyond that conferred by talc use alone, as shown in a recent study.

PTSD linked to increased risk of hypothyroidism among women

19 Nov 2019

Women with post-traumatic stress disorder (PTSD) are at increased risk of developing thyroid dysfunction, a study reports.

The study included 45,992 women from the ongoing Nurses’ Health Study II. Thirty percent of these women reported having no history of traumatic events, 50 percent reported being exposed to trauma with no PTSD symptoms, and 4 percent reported the highest number (6–7) of PTSD symptoms.

Relative to those who did not experience any trauma, women with the highest number of PTSD symptoms were more likely to have the highest somatotype at age 5 years, have a higher body mass index, smoke frequently, use oral contraceptives, be menopausal, and use ibuprofen medication and antidepressants.

Over a follow-up of 24 years, hypothyroidism occurred in 7,993 women and Graves’ hyperthyroidism in 847. Hypothyroidism showed a dose-response association with PTSD symptoms, with the incidence higher in the group of women presenting with a greater number of PTSD symptoms. This was not observed for Grave’s hyperthyroidism.

In multivariable Cox models, the hazard ratios for hypothyroidism were 1.08 (95 percent confidence interval [CI], 1.02–1.15) in women with trauma with no PTSD symptoms; 1.12 (95 percent CI, 1.04–1.21) in those with 1–3 PTSD symptoms; 1.23 (95 percent CI, 1.13–1.34) in those with 4–5 symptoms; and 1.26 (95 percent CI, 1.14–1.40) with 6–7 symptoms (p-trend<0.001).

The association persisted in sensitivity analyses restricted to outcomes with onset after 2008 when PTSD was assessed.

The present data underscore the importance of awareness for thyroid dysfunction in women with PTSD, according to researchers.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 2 days ago

Patients undergoing chemotherapy for breast or haematological cancers could potentially reduce their risk of chemotherapy-related cardiotoxicity with the use of angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor antagonists (ARBs), or beta-blockers as primary prevention, according to a systematic review and meta-analysis presented at the recent EuroEcho 2019 conference.

Tristan Manalac, 3 days ago
Users of electronic nicotine delivery systems are likely to have received a diagnosis of clinical depression in the past, according to a recent study.
Pearl Toh, 06 Dec 2019
Getting just under one extra hour of sleep per night can go a long way for the health of college students, who are often sleep-deprived, a study suggests.
6 days ago
While douching is not associated with the risk of ovarian cancer, the combination of talc and commercially available douches contributes to a modest increase in the risk of epithelial ovarian cancer beyond that conferred by talc use alone, as shown in a recent study.