Most Read Articles
Christina Lau, 23 Nov 2018

Use of a ginkgo biloba extract on top of standard preventive treatment is shown to improve cognitive function and overall condition after acute ischaemic stroke.

Psychological function predicts symptom severity, QOL in AF patients

15 Nov 2018

Psychological functioning consistently predicts symptom severity and health-related quality of life (hr-QOL) in atrial fibrillation (AF) patients with preserved left ventricular (LV) function, a recent study has found.

Researchers enrolled 78 consecutive patients (mean age 60±9 years; 77 percent male) with symptomatic AF and preserved LV systolic function, in whom two validated questionnaires were used to measure AF-related symptom burden and hr-QOL. The Global Measure of Perceived Stress Scale (PSS) and the Type D Personality Scale (TPDS) were used to measure psychological functioning.

Majority of the participants (64 percent; n=50) had moderate-to-severe AF-related symptoms, while 36 percent (n=26) had at most mild symptoms. Hr-QOL was significantly different between these two groups, with the former scoring significantly lower on the Short-Form Health Survey (38.9±10.1 vs 50.1±5.1; p<0.0001).

Moreover, those with moderate-to-severe symptoms scored significantly higher on the PSS (16.7±4.4 vs 5.4±4.4; p<0.0001) and were much more likely to manifest a Type D personality (20 of 50 vs 4 of 28; p=0.012), which denotes a high degree of negative affectivity and social inhibition.

Multivariable adjusted linear regression models showed that only higher scores on the PSS (coefficient, 0.63; p<0.001) and TDPS (coefficient, 0.55; p<0.001) were significant and independent predictors of more severe AF-specific symptoms.

Similarly, only PSS (coefficient, –0.45; p=0.002) and TDPS (coefficient, –0.48; p=0.005) were significantly predictive of worse hr-QOL.

Persistent AF, age, body mass index, obstructive sleep apnoea and exposure to flecainide were significant on unadjusted analyses but were all attenuated after adjusting for confounders.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Psychiatry - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Christina Lau, 23 Nov 2018

Use of a ginkgo biloba extract on top of standard preventive treatment is shown to improve cognitive function and overall condition after acute ischaemic stroke.