Most Read Articles
Roshini Claire Anthony, 5 days ago

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Psychological distress in pregnancy ups risk of respiratory infections in children

09 Feb 2019

Children whose mothers have experienced psychological distress, such as anxiety and depressive symptoms, during pregnancy are more likely to contract recurrent respiratory infections (RRI) by age 2 years, a recent study has found.

Researchers identified 204 children with (mean maternal age 31.5±4.4 years) and 1,014 without (mean maternal age 31.1±4.3 years) RRIs. Maternal psychological distress and parental relationship quality at 34 weeks of gestation were measured using The Edinburgh Postnatal Depression Scale (EPDS), Symptom Checklist-90 anxiety subscale (SCL90/Anxiety), the Pregnancy-Related Anxiety Questionnaire–Revised 2 (PRAQ-R2) and the Revised Dyadic Adjustment Scale (RDAS).

Mothers in the RRI group reported significantly higher scores on all scales, suggesting that symptoms of depression (p<0.001), anxiety (p=0.04) and pregnancy-specific anxiety (p=0.001) were all elevated, while parental relationship satisfaction was reduced (p=0.008).

Postnatal distress levels were similar. Compared with mothers in the comparison group, those in the RRI group reported significantly greater depressive (p=0.001) and anxiety (p=0.03) symptoms, while relationship satisfaction with the child at 2 years of age remained lower (p=0.003).

Logistic regression analysis further confirmed that scores in the EPDS (odd ratio [OR], 1.24; 95 percent CI, 1.08–1.44; p=0.003) and RDAS (OR, 1.32; 1.01–1.58; p=0.003) at 34 weeks of gestation were significantly and positively correlated with offspring RRIs at age 2 years.

The same was true for the SCL90/Anxiety (OR, 1.40; 1.01–1.76; p=0.006) and the PRAQ-R2 (OR, 1.28; 1.11–1.47; p=0.001). The above relationships remained significant even after controlling for the number of siblings and the duration of breastfeeding.

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Most Read Articles
Roshini Claire Anthony, 5 days ago

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Stephen Padilla, 6 days ago
Implementation of the collaborative care in a rheumatoid arthritis (RA) clinic has led to improvements in nonbiologic disease-modifying antirheumatic drugs (nb-DMARDs) optimization, adherence to safety recommendations on nb-DMARD monitoring and detection of adverse drug events in RA patients, according to a Singapore study.
Pearl Toh, 6 days ago
Use of menopausal hormone therapy (MHT) was associated with a significantly increased risk of invasive breast cancer, which became progressively greater with longer duration of use, a meta-analysis of worldwide prospective epidemiological studies has shown.
5 days ago
Blood pressure (BP) in children is influenced by early-life exposure to several chemicals, built environment and meteorological factors, suggests a study.