Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
5 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.
6 days ago
Prevention of glucocorticoid-induced osteoporosis (GIOP) and postmenopausal osteoporosis (PMOP) remains inadequate in patients with rheumatoid arthritis (RA), as shown in a study that evaluated the implementation of the 2003 and 2014 French guidelines on the prevention and treatment of GIOP and the 2012 update of the French guidelines for the treatment of PMOP.

Psoriatic patients on biologic therapy not likely to be diagnosed with psychiatric illness

26 Aug 2019

The risk of several medical and psychiatric illnesses is higher in patients with psoriasis, but those prescribed biologic agents are less likely to develop the latter as compared to those not prescribed medications, according to a study.

“Most likely because of treatment selection, individuals with psoriasis prescribed biologic therapy are not currently at increased risk of a psychiatric outcome,” the investigators said.

This retrospective electronic medical records cohort study sought to determine if patients with psoriasis or those exposed to biologics were more likely to develop a psychiatric illness.

A history of several medical (eg, cardiovascular diseases) and psychiatric (depression, suicide) illnesses was significantly more common among individuals with psoriasis than those without. Among patients with psoriasis, prescription of a biologic therapy resulted in a significantly lower likelihood of being diagnosed with a psychiatric illness (hazard ratio [HR], 0.52, 95 percent CI, 0.51–0.53; p<0.0001).

“With respect to any psychiatric illness, this finding was confirmed when comparing biologic therapy vs methotrexate treatment (HR, 0.80, 0.76–0.84; p<0.0001),” the investigators said.

A recent study also suggests that patients with moderate-to-severe psoriasis have a higher prevalence of psychiatric disorders than the general population, with a substantial incremental burden of treated anxiety or depression. Additionally, treatments that improve psychiatric symptoms appear to benefit patients and reduce their economic burden. [J Med Econ 2019;doi:10.1080/13696998.2019.1638788]

The present study was limited by findings that were likely attributable to treatment selection bias.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
5 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.
6 days ago
Prevention of glucocorticoid-induced osteoporosis (GIOP) and postmenopausal osteoporosis (PMOP) remains inadequate in patients with rheumatoid arthritis (RA), as shown in a study that evaluated the implementation of the 2003 and 2014 French guidelines on the prevention and treatment of GIOP and the 2012 update of the French guidelines for the treatment of PMOP.