Most Read Articles
Pank Jit Sin, 02 May 2018
Leptospirosis is an endemic disease in Malaysia, but may be missed as doctors are not looking for it. 
Dr. Joseph Delano Fule Robles, 05 Dec 2017

Results of a study conducted by the Chinese University of Hong Kong (CUHK) revealed that patients who recovered from hepatitis B virus (HBV) infection are still at risk for hepatocellular carcinoma (HCC). 

30 Mar 2018
A US study suggests that expanding HIV screening to reduce undiagnosed infections and increasing access to care and treatment to achieve viral suppression are important to lessen HIV transmission. It is also imperative that prevention methods, such as condoms and pre-exposure prophylaxis, be easily accessed, particularly among young men who have sex with men (MSM) and MSM of colour.
Saras Ramiya, 6 days ago
The National Institutes of Health (NIH) and International Medical University (IMU) strengthens their research collaboration with the recent signing of a Memorandum of Understanding (MoU).

Psoriasis tied to greater risk of serious infections

24 Jul 2018
Psoriasis raises the risk of serious infections regardless of other traditional risk factors for infections, a recent UK study has shown.

Accessing an electronic medical records database, researchers assessed 187,258 patients with mild psoriasis (mean age 46.4±17.5 years; 48.4 percent male) and 12,442 patients with moderate-to-severe disease (mean age 49.4±15.1 years; 48.7 percent male). Cox proportional hazards regression analyses were performed to evaluate the risk of serious infection according to psoriasis severity.

The incidence rate of psoriasis in patients without psoriasis (n=954,315) was 78.5 per 10,000 person-years, which was lower than that in all psoriasis patients (88.9 per 10,000 person-years). Analysis by disease severity showed that incidence rate was highest in those with moderate-to-severe vs mild psoriasis (145.7 vs 85.7 per 10,000 person-years).

This trend was confirmed through multivariable analysis, which showed that compared with no psoriasis controls, patients with moderate-to-severe psoriasis (adjusted hazard ratio [HR], 1.63; 95 percent CI, 1.52–1.75) are at a greater risk of serious infections than those with mild disease (adjusted HR, 1.18; 1.16–1.21).

The findings were further confirmed in a subsequent analysis of a second cohort that consisted of 83,543 no psoriasis controls, 4,437 mild psoriasis patients and 4,132 moderate-to-severe psoriasis patients.

Incidence of serious infections was likewise greatest in the mild-to-moderate psoriasis group relative to the mild and no psoriasis groups (110.9 vs 97.6 and 75.6 per 10,000 person-years; adjusted HR, 1.27; 1.10–1.47).

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Most Read Articles
Pank Jit Sin, 02 May 2018
Leptospirosis is an endemic disease in Malaysia, but may be missed as doctors are not looking for it. 
Dr. Joseph Delano Fule Robles, 05 Dec 2017

Results of a study conducted by the Chinese University of Hong Kong (CUHK) revealed that patients who recovered from hepatitis B virus (HBV) infection are still at risk for hepatocellular carcinoma (HCC). 

30 Mar 2018
A US study suggests that expanding HIV screening to reduce undiagnosed infections and increasing access to care and treatment to achieve viral suppression are important to lessen HIV transmission. It is also imperative that prevention methods, such as condoms and pre-exposure prophylaxis, be easily accessed, particularly among young men who have sex with men (MSM) and MSM of colour.
Saras Ramiya, 6 days ago
The National Institutes of Health (NIH) and International Medical University (IMU) strengthens their research collaboration with the recent signing of a Memorandum of Understanding (MoU).