Most Read Articles
Elvira Manzano, 2 days ago
Monthly injections of the PCSK9* monoclonal antibody evolocumab effectively reduced plasma LDL-cholesterol (LDL-C), often referred to as the bad cholesterol, in teenagers with heterozygous familial hypercholesterolaemia (HeFH) already taking statins, with or without ezetimibe, the HAUSER-RCT has shown.
Jairia Dela Cruz, 2 days ago
For individual with type 2 diabetes, losing weight is everything when it comes to improving the metabolic function, and it matters little whether this is achieved by dieting or undergoing bariatric surgery, according to a small study.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
2 days ago
In patients with type 2 diabetes (T2D), postprandial hyperglycaemia and hypertriglyceridemia worsens survival outlook, finds a new study.

Pruritus lacks convenient tools for reliable assessment

21 Dec 2019

There remains no single, convenient tool available for use as a gold standard in evaluation of quality of life in pruritus, a new study has shown.

The study included 419 patients (mean age, 46.58±17.42 years; 51.3 percent male) with chronic pruritus. Researchers used four different evaluation tools―the visual analogue scale (VAS), the numeric rating scale (NRS), the verbal rating scale (VRS) and the itch severity scale (ISS)―and assessed their correlation with the ItchyQoL, a quality of life measurement instrument specific for pruritus.

Patients had had pruritus for a mean of 150.3±266.6 weeks; 72.8 percent (n=305) were on systemic treatment for itch. Seventy patients (18.0 percent) noted no pruritus improvement even after medication.

VAS, NRS and VRS were strongly correlated among each other during the initial visit. The Spearman’s correlation coefficient, for example, was 0.86 between VAS and NRS. It was 0.81 between NRS and VRS and 0.72 between VAS and VRS. ISS, however, was poorly correlated with these three scales, with Spearman’s correlation coefficient values ranging from 0.54 to 0.62.

These trends persisted until 3 hours after the initial assessment. VAS, NRS and VRS remained strongly associated with each other while ISS was not.

Despite these, ISS emerged as the most highly correlated with ItchyQoL upon initial assessment (Spearman’s coefficient, 0.73). VAS, NRS and VRS performed poorly in comparison, with Spearman’s coefficient values 0.45, 0.49 and 0.47, respectively. This persisted until the 3-hour follow-up.

“In this study, ISS showed good retest reliability and the highest correlation with ItchyQoL compared with three unidimensional scales. However, it is too time consuming for routine clinical use,” said researchers.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Elvira Manzano, 2 days ago
Monthly injections of the PCSK9* monoclonal antibody evolocumab effectively reduced plasma LDL-cholesterol (LDL-C), often referred to as the bad cholesterol, in teenagers with heterozygous familial hypercholesterolaemia (HeFH) already taking statins, with or without ezetimibe, the HAUSER-RCT has shown.
Jairia Dela Cruz, 2 days ago
For individual with type 2 diabetes, losing weight is everything when it comes to improving the metabolic function, and it matters little whether this is achieved by dieting or undergoing bariatric surgery, according to a small study.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
2 days ago
In patients with type 2 diabetes (T2D), postprandial hyperglycaemia and hypertriglyceridemia worsens survival outlook, finds a new study.