Most Read Articles
08 Jun 2018
Passive smoking at home and in the workplace as well as having a family history of diabetes mellitus increase the risk of gestational diabetes mellitus (GDM), according to a recent China study.
Pearl Toh, 05 Jun 2018
Asian patients with end-stage renal failure (ESRF) had almost triple the risk of death within 1 year after hip fracture surgery, making ESRF an independent predictor for 1-year mortality, a recent study found.
Stephen Padilla, 06 Jun 2018
The amount of added sugars in the diet, especially when present in processed foods, appears to increase the risk of frailty in older people, a recent study suggests. Low levels of physical activity and unintentional weight loss are the frailty components more closely associated with added sugars.
Dr Joslyn Ngu, 5 days ago

The transcultural Diabetes Nutrition Algorithm (tDNA) which involves a structured low-calorie meal plan, diabetes-specific meal replacements and enhanced physical activity, is effective for weight loss in patients with type 2 diabetes, a local study shows. [BMJ Open Diabetes Res Care 2017;5(1):e000384. Doi:10.1136/bmjdrc-2016-000384th]

Product Highlight - Invokana

16 Dec 2016
INVOKANA – Canagliflozin hemihydrate 100 mg and 300 mg FC tab – Johnson & Johnson (Janssen)
  • INVOKANA demonstrated statistically significant glycated haemoglobin A1c (HbA1c) reductions and helped more patients achieve the ADA-recommended HbA1c goal of <7%1,4.
  • Only Invokana 300 mg demonstrated greater reductions in vs HbA1c sitagliptin 100 mg2.
  • INVOKANA results in the excretion of approximately 77 grams to 119 grams of glucose per day3.
  • INVOKANA provided greater reductions in body weight and systolic blood pressure vs placebo3.
  • INVOKANA showed good tolerability profile with the following most common adverse reactions – female genital mycotic infection, urinary tract infection (UTI) and increased urination3.
References:
1. Stenlöf K, Cefalu WT, Kim KA, et al. Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise. Diabetes Obes Metab.2013;15(4):372-382.
2. Schernthaner G, Gross JL, Rosenstock J, et al. Canagliflozin compared with sitagliptin for patients with type 2 diabetes who do not have adequate glycemic control with metformin plus sulfonylurea: a 52-week randomized trial. Diabetes Care. 2013;36:2508-2515.
3. Invokana_Approved Prescribing Information_Malaysia_EU SmPC vJan2016.
4: American Diabetes Association. Standards of medical care in diabetes—2016. Diabetes Care. 2016; 39(Supplement 1): S39-S46.

Further information is available in Section 11b, New In This Issue and mims.com
Full prescribing information is available upon request.

MKT-CAN-MY-0026Creation Date: October 2016

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Most Read Articles
08 Jun 2018
Passive smoking at home and in the workplace as well as having a family history of diabetes mellitus increase the risk of gestational diabetes mellitus (GDM), according to a recent China study.
Pearl Toh, 05 Jun 2018
Asian patients with end-stage renal failure (ESRF) had almost triple the risk of death within 1 year after hip fracture surgery, making ESRF an independent predictor for 1-year mortality, a recent study found.
Stephen Padilla, 06 Jun 2018
The amount of added sugars in the diet, especially when present in processed foods, appears to increase the risk of frailty in older people, a recent study suggests. Low levels of physical activity and unintentional weight loss are the frailty components more closely associated with added sugars.
Dr Joslyn Ngu, 5 days ago

The transcultural Diabetes Nutrition Algorithm (tDNA) which involves a structured low-calorie meal plan, diabetes-specific meal replacements and enhanced physical activity, is effective for weight loss in patients with type 2 diabetes, a local study shows. [BMJ Open Diabetes Res Care 2017;5(1):e000384. Doi:10.1136/bmjdrc-2016-000384th]