Most Read Articles
Prof. Cheuk-Chun Szeto, Dr. Winston W. S. Fung, 25 Jan 2018
A 65-year-old lady with a background of type 2 diabetes, hyperlipidaemia and chronic immune thrombocytopenia presented to us with a 2-week history of generalized malaise and myalgia. Shortly after the onset of myalgia, she was noted to have reduced urine output and the urine was described as dark in colour. Her regular medications included prednisolone, danazol, simvastatin, metformin, and human insulin. Upon further questioning, the patient admitted that her compliance to simvastatin and danazol used to be poor. However, she recently started to take both medications regularly after repeated education.
Pearl Toh, 30 Jan 2018
Use of statins may not be neuroprotective, in contrast to findings from previous observational studies. On the contrary, fungus-derived or lipophilic statins appeared to be associated with a slightly increased risk of Alzheimer's disease (AD) compared with synthetic and hydrophilic statins, suggests a new study based on real-world clinical practice data.
26 Dec 2017
Supplementation with omega-3 fatty acids in combination with rosuvastatin may yield significant reductions in triglycerides and nonhigh-density lipoprotein (HDL) cholesterol as compared with rosuvastatin monotherapy, according to data from the ROMANTIC (rosuvastatin-omacor in residual hypertriglyceridemia) trial.
Rachel Soon, 21 Feb 2018

MIMS Pharmacist sits down with pharmacist researcher Dr Mai Chun Wai to find out more about his work in drug discovery, including his investigations of Antarctic soil microorganisms.

Product Highlight - Fluarix Tetra

30 Nov 2017

Fluarex Tetra - Inactivated quadrivalent influenza vaccine (split virion) vaccine (inj) 0.5 mL - GlaxoSmithKline

Flu vaccines help protect millions, but do you know there is a coverage gap?1
Choose Fluarix Tetra for your patients

  • The gap in B strain coverage from TIVs* can leave your patients unprotected.2,3,4,5
  • QIVs* can help to close the B strain coverage gap6,7
  • Fluarix Tetra is a QIV* which is generally well tolerated, is easy to administer, helps to increase protection against influenza B over TIVs*, closes the coverage gap to protect your patients and has robust data in high risk patients group6,8

*TIV: Trivalent Influenza Vaccine,QIV: Quadrivalent Influenza Vaccine

References:
1. United States Centers for Disease Control and Prevention. Quadrivalent Influenza Vaccine. Available at: https://www.cdc.gov/flu/protect/vaccine/quadrivalent.htm. Accessed on:3March 2017
2. Ambrose CS, Levin MJ. The rationale for quadrivalent infuenza vaccines Hum Vaccin Immunother 2012;8: 81-88
3. Jumat MR, et al. Genetic characterisation of in_uenza B viruses detected in Singapore, 2004 to 2009 BMC Res Notes 2014;7: 863
4. Belshe RB. The need for quadrivalent vaccine against seasonal influenza Vaccine 2010;28: D45–D53 5. Reed C, et al. Public health impact of including two lineages of influenza B in a quadrivalent seasonal influenza vaccine Vaccine 2012;30: 1993-1998
6. GSK. Fluarix Tetra Quadrivalent influenza vaccine (split virion, inactivated). (2017).
7. Domachowske JB, Pankow-Culot H, Bautista M et al. A randomized trial of candidate inactivated quadrivalent influenza vaccine versus trivalent influenza vaccines in children aged 3–17 years. J Infect Dis. 2013; 207: 1878–1887.
8. Kieninger D, Sheldon E, Lin W, et al. Immunogenicity, reactogenicity and safety of an inactivated quadrivalent influenza vaccine candidate versus inactivated trivalent influenza vaccine: a phase III, randomized trial in adults aged 18 years. BMC Infectious Diseases 2013; 13:343.

Further information is available in section 12b, New in This Issue and mims.com.
Full prescribing information is available upon request.                        

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Most Read Articles
Prof. Cheuk-Chun Szeto, Dr. Winston W. S. Fung, 25 Jan 2018
A 65-year-old lady with a background of type 2 diabetes, hyperlipidaemia and chronic immune thrombocytopenia presented to us with a 2-week history of generalized malaise and myalgia. Shortly after the onset of myalgia, she was noted to have reduced urine output and the urine was described as dark in colour. Her regular medications included prednisolone, danazol, simvastatin, metformin, and human insulin. Upon further questioning, the patient admitted that her compliance to simvastatin and danazol used to be poor. However, she recently started to take both medications regularly after repeated education.
Pearl Toh, 30 Jan 2018
Use of statins may not be neuroprotective, in contrast to findings from previous observational studies. On the contrary, fungus-derived or lipophilic statins appeared to be associated with a slightly increased risk of Alzheimer's disease (AD) compared with synthetic and hydrophilic statins, suggests a new study based on real-world clinical practice data.
26 Dec 2017
Supplementation with omega-3 fatty acids in combination with rosuvastatin may yield significant reductions in triglycerides and nonhigh-density lipoprotein (HDL) cholesterol as compared with rosuvastatin monotherapy, according to data from the ROMANTIC (rosuvastatin-omacor in residual hypertriglyceridemia) trial.
Rachel Soon, 21 Feb 2018

MIMS Pharmacist sits down with pharmacist researcher Dr Mai Chun Wai to find out more about his work in drug discovery, including his investigations of Antarctic soil microorganisms.