Most Read Articles
Elaine Soliven, 4 days ago

Switching from efavirenz/emtricitabine/tenofovir disoproxil fumarate (EFV/FTC/TDF) to the new bictegravir/ emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) regimen maintained high rates of virological suppression in adults who are living with HIV*, according to a study presented at AIDS 2020.

3 days ago
Among individuals with abdominal obesity, drinking beverages with artificial sweeteners (ASBs) or no sugar (USBs) instead of sugar-sweetened beverages (SSBs) helps lose body weight, a study has found. However, USBs have a more favourable effect on sweet taste preference compared with ASBs.
Stephen Padilla, 4 days ago
Pre-exposure prophylaxis (PrEP) containing either long-acting injectable cabotegravir (CAB) or tenofovir/emtricitabine (TDF/FTC) is safe and effective for transgender women (TGW) and cisgender men who have sex with men (MSM), but CAB results in a much lower HIV incidence compared to TDF/FTC, results of the HIV Prevention Trials Network (HPTN) 083 have shown.
Jairia Dela Cruz, 3 days ago
Monthly prophylaxis with the fixed-dose combination of naphthoquine-azithromycin (NQAZ) is well tolerated and confers significant protection against infection with Plasmodium parasites among individuals residing in malaria-endemic areas in Southeast Asia, as shown in the results of a phase III trial.

Preventive vigabatrin has long-term epilepsy benefits in kids with sclerosis

16 Dec 2019
Multiple Sclerosis (MS) is a debilitating disease, in which nerve damage affects communications between the brain and body. HSCT could provide the therapeutic answer for MS patients.

Preventive treatment with antiepileptic agents in infants with tuberous sclerosis complex helps improve epilepsy control in the long-term, a recent study has found.

Researchers conducted a prospective, nonrandomized clinical trial on 14 infants with tuberculosis sclerosis complex. Preventive vigabatrin medication was initiated upon the detection of epileptic discharges on serial electroencephalography. Long-term outcomes were compared against a parallel group of 31 infants who received medication only after the onset of clinical seizures.

In the arm that received preventive medication, the median intelligence quotient (IQ) was 94, while 21 percent (n=14) of the participants had moderate or severe intellectual disabilities. Two children in this group had no consent for IQ assessment but nevertheless showed no evidence of epileptogenesis or seizures. They also appeared to have normal cognitive development and were able to attend regular primary school without special needs.

In the comparator group, the median IQ was 46, and 72 percent were diagnosed with intellectual disability. Six (24 percent) had severe and three (12 percent) had profound disability.

Comparison between groups revealed a significant benefit in favour of preventive treatment, both in terms of neuropsychologic measures (p<0.03) and the prevalence of intellectual disability (p=0.003).

The same was true for epilepsy outcomes. At the final follow-up visit, almost all of those who received standard medication developed clinical seizures, as opposed to only half in the preventive-treatment group (96 percent vs 50 percent; p=0.001).

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Most Read Articles
Elaine Soliven, 4 days ago

Switching from efavirenz/emtricitabine/tenofovir disoproxil fumarate (EFV/FTC/TDF) to the new bictegravir/ emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) regimen maintained high rates of virological suppression in adults who are living with HIV*, according to a study presented at AIDS 2020.

3 days ago
Among individuals with abdominal obesity, drinking beverages with artificial sweeteners (ASBs) or no sugar (USBs) instead of sugar-sweetened beverages (SSBs) helps lose body weight, a study has found. However, USBs have a more favourable effect on sweet taste preference compared with ASBs.
Stephen Padilla, 4 days ago
Pre-exposure prophylaxis (PrEP) containing either long-acting injectable cabotegravir (CAB) or tenofovir/emtricitabine (TDF/FTC) is safe and effective for transgender women (TGW) and cisgender men who have sex with men (MSM), but CAB results in a much lower HIV incidence compared to TDF/FTC, results of the HIV Prevention Trials Network (HPTN) 083 have shown.
Jairia Dela Cruz, 3 days ago
Monthly prophylaxis with the fixed-dose combination of naphthoquine-azithromycin (NQAZ) is well tolerated and confers significant protection against infection with Plasmodium parasites among individuals residing in malaria-endemic areas in Southeast Asia, as shown in the results of a phase III trial.