Most Read Articles
Stephen Padilla, 02 Oct 2019
Baseline body mass index (BMI) and, to a lesser extent, school socioeconomic status are associated with subsequent weight status in schoolchildren, according to a study. Lifestyle behaviours show a lower effect as compared with prior BMI, but children with a healthier lifestyle have a reduced risk of overweight and obesity at follow-up.
04 Sep 2019
The use of iron-fortified formula milk in infants between 6–12 months of age may lead to poorer cognitive outcomes, a recent study has shown.
Audrey Abella, 07 May 2019
Use of electronic vapour products (EVP), or vaping, has been associated with an increased likelihood of engaging in sexual and substance-use risk behaviours among US teenagers, according to data from the 2017 National Youth Risk Behaviour Survey presented at the Paediatric Academic Societies (PAS) 2019 Meeting.
Jairia Dela Cruz, 04 Sep 2019
Parenteral antibiotic therapy duration for bacteraemic urinary tract infection (UTI) in young infants may be safely shortened, according to a recent study showing that recurrence and readmission or emergency department revisitation rates are comparable between a ≤7-day and a longer therapy course.

Preterm birth linked to components of metabolic syndrome in adulthood

08 Jul 2019

Preterm birth is associated with the risk of metabolic syndrome components and cardiovascular disease in adult life, a recent meta-analysis has found.

Applying the selection criteria resulted in 43 studies eligible for analysis. The overall sample included 18,295 adults born preterm (mean age, 19.4±5.1 years; 16,119 males) and 294,063 born term (284,788 males). Among the outcomes assessed were body mass index, fat mass, waist-to-hip ratio, blood pressure (BP), pulse wave velocity, fating glucose and insulin, and lipid profile.

The percentage of fat mass was significantly higher in adults born premature, both in random (mean difference, 1.5 percent, 95 percent CI, 0.1–2.8; p=0.03) and fixed (mean difference, 1.2 percent, 0.3–2.1 percent; p=0.009) effect models. Body mass index, waist circumference and waist-to-hip ratio were comparable between birth groups.

Systolic (SBP; random mean difference, 4.2 mm Hg, 3.0–5.5; p<0.0001) and diastolic (DBP; random mean difference, 2.3 mm Hg, 1.2–3.3; p<0.0001) BP were also significantly elevated in those who were born premature. The same was true for 24-hour SBP (random mean difference, 4.6 mm Hg, 2.0–7.2; p<0.001) and DBP (random mean difference, 1.7 mm Hg, 0.9–2.5; p<0.001).

Fasting glucose in both random (mean difference, 0.07 mmol/L, 0.02–0.1; p=0.01) and fixed (mean difference, 0.06 mmol/L, 0.02–0.1; p=0.008) models, as well as fasting total cholesterol (random mean difference, 0.2 mmol/L, 0.0–0.3; p=0.05; fixed mean difference, 0.2 mmol/L, 0.04–0.3; p=0.008) were similarly higher in those preterm. Fasting insulin achieved significance only in random effects model.

There were no significant between-group differences in terms of fasting high- and low-density lipoprotein, triglycerides, carotid intima-media thickness, flow mediated dilation, and pulse wave velocity.

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Most Read Articles
Stephen Padilla, 02 Oct 2019
Baseline body mass index (BMI) and, to a lesser extent, school socioeconomic status are associated with subsequent weight status in schoolchildren, according to a study. Lifestyle behaviours show a lower effect as compared with prior BMI, but children with a healthier lifestyle have a reduced risk of overweight and obesity at follow-up.
04 Sep 2019
The use of iron-fortified formula milk in infants between 6–12 months of age may lead to poorer cognitive outcomes, a recent study has shown.
Audrey Abella, 07 May 2019
Use of electronic vapour products (EVP), or vaping, has been associated with an increased likelihood of engaging in sexual and substance-use risk behaviours among US teenagers, according to data from the 2017 National Youth Risk Behaviour Survey presented at the Paediatric Academic Societies (PAS) 2019 Meeting.
Jairia Dela Cruz, 04 Sep 2019
Parenteral antibiotic therapy duration for bacteraemic urinary tract infection (UTI) in young infants may be safely shortened, according to a recent study showing that recurrence and readmission or emergency department revisitation rates are comparable between a ≤7-day and a longer therapy course.