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Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Elvira Manzano, 3 days ago

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Preoperative illnesses do not increase risk of complications after hypospadias repair

11 Feb 2019

Children with preoperative illnesses, such as common cold, are not at increased risk for postoperative complications, according to a recent study. Preoperative illnesses that are not severe enough to postpone surgery may even have a protective effect, particularly for postoperative infections.

“Consequently, there is no reason to alter preoperative screening,” the authors said.

A total of 681 boys were included, of whom 22 percent had preoperative illnesses and 14 percent had postoperative complications. Children with preoperative illnesses had fewer postoperative complications within 2 months (n=13; 9 percent) than those without preoperative illnesses (n=79; 16 percent), resulting in a 50-percent risk reduction (odds ratio [OR], 0.49; 95 percent CI, 0.26–0.93).

Of note, preoperative infections (eg, common cold, fever and ear infection) were associated with a lower risk of postoperative infections, including wound and urinary tract infections (OR, 0.37; 0.14–0.98). Results for complications were similar within 1 year.

This retrospective cohort study obtained data from 681 children with anterior or middle-type hypospadias that had initial 1-stage repair in the period 1983–2012 in The Netherlands.

Multivariable logistic regression analyses were used to analyse the associations between common illnesses, such as common cold, fever and ear infection, within 2 weeks before repair, and postoperative complications, such as urethrocutaneous fistula, wound dehiscence and stenosis, within 2 months and 1 year after surgery.

“Preoperative illnesses might induce immunosuppression and subsequently increase morbidity after surgery. Several studies have tried to identify risk factors for complications after hypospadias correction, but effects of illnesses in the weeks just before surgery are unknown,” the authors noted.

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Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Elvira Manzano, 3 days ago

The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.

Pearl Toh, 4 days ago
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.
14 Sep 2019
In type 2 diabetes patients taking sulfonylureas, hypoglycaemia duration is longer at night and is inversely correlated with the level of glycated haemoglobin (HbA1c), a new study reports.